474780 Sigma-AldrichMG-115 - CAS 133407-86-0 - Calbiochem
Potent reversible proteasome inhibitor (Ki = 21 nM and 35 nM for 20S and 26S proteasome, respectively).
More>> Potent reversible proteasome inhibitor (Ki = 21 nM and 35 nM for 20S and 26S proteasome, respectively). Less<<MG-115 - CAS 133407-86-0 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Synonyms: Carbobenzoxy-L-leucyl-L-leucyl-L-norvalinal, Z-LL-Nva-CHO, Proteasome Inhibitor XII
Recommended Products
Overview
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Key Spec Table
| CAS # | Empirical Formula |
|---|---|
| 133407-86-0 | C₂₅H₃₉N₃O₅ |
Products
| Catalogue Number | Packaging | Qty/Pack | |
|---|---|---|---|
| 474780-5MG | Plastic ampoule | 5 mg |
| Product Information | |
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| CAS number | 133407-86-0 |
| ATP Competitive | N |
| Form | White solid |
| Hill Formula | C₂₅H₃₉N₃O₅ |
| Chemical formula | C₂₅H₃₉N₃O₅ |
| Reversible | Y |
| Structure formula Image | |
| Quality Level | MQ100 |
| Applications |
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| Biological Information | |
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| Primary Target | 20S proteasome |
| Primary Target K<sub>i</sub> | 21 nM and 35 nM for 20S and 26S proteasome, respectively |
| Purity | ≥90% by HPLC |
| Physicochemical Information | |
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| Cell permeable | N |
| Peptide Sequence | Z-Leu-Leu-Nva-CHO |
| Dimensions |
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| Materials Information |
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| Toxicological Information |
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| Safety Information according to GHS |
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| Product Usage Statements |
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| Supplemental Information |
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| Specifications |
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| Global Trade Item Number | |
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| Catalogue Number | GTIN |
| 474780-5MG | 04055977185447 |
Documentation
MG-115 - CAS 133407-86-0 - Calbiochem SDS
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MG-115 - CAS 133407-86-0 - Calbiochem Certificates of Analysis
| Title | Lot Number |
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| 474780 |
References
| Reference overview |
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| Lopes, U.G., et al. 1997. J. Biol. Chem. 272, 12893. Lee, D.H., and Goldberg, A.L. 1996. J. Biol. Chem. 271, 27280. Palombella, V.J., et al. 1994. Cell 78, 773. Rock, K.L., et al. 1994. Cell 78, 761. Vinitsky, A., et al. 1992. Biochemistry 31, 9421. |
Brochure
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| Caspases and other Apoptosis Related Tools Brochure |
| Proteasomes Technical Bulletin |