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434692 Leukotriene C₄ - CAS 72025-60-6 - Calbiochem

Leukotriene C₄ - CAS 72025-60-6 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: LTC₄, 5(S)-Hydroxy-6(R)-S-glutathionyl-7-trans-9-trans-11-cis-14-cis-eicosatetraenoic Acid

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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
72025-60-6C₃₀H₄₇N₃O₉S
Description
Overview

This product has been discontinued.



Implicated in renal vasoconstriction associated with sepsis. Also plays a role in bronchioconstriction. Produced by conjugation of LTA4 with reduced glutathione. Reported to be a tight binding inhibitor of microsomal glutathione transferase-1. Has been implicated in pathophysiology of asthma.
Catalogue Number434692
Brand Family Calbiochem®
SynonymsLTC₄, 5(S)-Hydroxy-6(R)-S-glutathionyl-7-trans-9-trans-11-cis-14-cis-eicosatetraenoic Acid
References
ReferencesBannenberg, G., et al. 1999. J. Biol. Chem. 274, 1994.
Shimizu, T., et al. 1994. Pediatr. Pulmonol. 18, 129.
Product Information
CAS number72025-60-6
ATP CompetitiveN
FormLiquid
FormulationIn MeOH:NH₄OAc buffer (65:35), pH 5.6.
Hill FormulaC₃₀H₄₇N₃O₉S
Chemical formulaC₃₀H₄₇N₃O₉S
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetMicrosomal glutathione transferase-1
Purity≥98% by HPLC
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
RTECSMB9143500
Safety Information
R PhraseR: 11-23/24/25-39/23/24/25

Highly flammable.
Toxic by inhalation, in contact with skin and if swallowed.
Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed.
S PhraseS: 16-7-36/37-45

Keep away from sources of ignition - No Smoking.
Keep container tightly closed.
Wear suitable protective clothing and gloves.
In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
Product Usage Statements
Storage and Shipping Information
Ship Code Dry Ice Only
Toxicity Flammable
Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Storage ≤ -70°C
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquor and freeze (-70°C).
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
434692 0

Documentation

Leukotriene C₄ - CAS 72025-60-6 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

Leukotriene C₄ - CAS 72025-60-6 - Calbiochem Certificates of Analysis

TitleLot Number
434692

References

Reference overview
Bannenberg, G., et al. 1999. J. Biol. Chem. 274, 1994.
Shimizu, T., et al. 1994. Pediatr. Pulmonol. 18, 129.

Brochure

Title
Bioactive Lipids Technical Bulletin
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision14-May-2008 RFH
SynonymsLTC₄, 5(S)-Hydroxy-6(R)-S-glutathionyl-7-trans-9-trans-11-cis-14-cis-eicosatetraenoic Acid
DescriptionImplicated in renal vasoconstriction associated with sepsis. Also plays a role in bronchioconstriction. Produced by conjugation of LTA4 with reduced glutathione. Reported to be a tight binding inhibitor of microsomal glutathione transferase-1. Has been implicated in pathophysiology of asthma.
FormLiquid
FormulationIn MeOH:NH₄OAc buffer (65:35), pH 5.6.
CAS number72025-60-6
RTECSMB9143500
Chemical formulaC₃₀H₄₇N₃O₉S
Structure formulaStructure formula
Purity≥98% by HPLC
Storage ≤ -70°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquor and freeze (-70°C).
Toxicity Flammable
Merck USA index14, 5455
ReferencesBannenberg, G., et al. 1999. J. Biol. Chem. 274, 1994.
Shimizu, T., et al. 1994. Pediatr. Pulmonol. 18, 129.