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101587 L-Arginine

Overview

Replacement Information

Key Spec Table

CAS #EC NumberHill FormulaMolar MassGrade Value
74-79-3200-811-1C₆H₁₄N₄O₂174.2 g/molPh Eur,ChP,JP,USP

Products

Catalogue NumberPackaging Qty/Pack
1015870001 Plastic bottle 3 x 1 kg
1015870101 Plastic bottle 100 g
1015871000 Plastic bottle 1 kg
1015879010 Plastic drum 10 kg
Description
Catalogue Number101587
SynonymsArg
References
Product Information
CAS number74-79-3
EC number200-811-1
GradePh Eur,ChP,JP,USP
Hill FormulaC₆H₁₄N₄O₂
Molar Mass174.2 g/mol
HS Code2925 29 19
Structure formula ImageStructure formula Image
Quality LevelMQ500
Applications
Biological Information
Physicochemical Information
Density1.1 g/cm3
Melting Point223 - 224 °C (decomposition)
pH value11.4 (100 g/l, H₂O, 20 °C)
Vapor pressure<0.1 hPa (25 °C)
Bulk density640 kg/m3
Solubility148.7 g/l
Dimensions
Materials Information
Toxicological Information
LD 50 oralLD50 Rat > 5110 mg/kg
Safety Information according to GHS
RTECSCF1934200
Storage class10 - 13 Other liquids and solids
WGKWGK 1 slightly hazardous to water
Disposal3
Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.
Safety Information
Categories of dangerirritant
Product Usage Statements
Storage and Shipping Information
StorageStore at +2°C to +30°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Assay (perchloric acid titration, calculated on dried substance)99.0 - 101.0 %
Identity (IR-spectrum)passes test
Identity (TLC)passes test
Identity (specific rotation)passes test
Appearancewhite to almost white, crystalline powder or colorless crystals
Appearance of solution (50 g/l; water)clear and not more intense in color than reference solution BY₆
Appearance of solution (100 g/l, CO₂-free water)clear and colorless
Transmittance of solution (100 g/l, water)≥ 98.0 %
Spec. rotation (α 20/D, 80 g/l, hydrochloric acid 250 g/l, calc. on dried substance)+25.5 to +28.5
Spec. rotation (α 20/D, 80 g/l, hydrochloric acid 6 mol/l, calc. on dried substance)+26.9 to +27.9
Spec. rotation (α 25/D, 80 g/l, hydrochloric acid 6 mol/l, calc. on dried substance)+26.3 to +27.7
Spec. rotation (α 20/D, 80 g/l, hydrochloric acid 6 mol/l,previously dried substance)+26.9 to +27.9
pH (100 g/l, CO₂-free water)10.5 - 12.0
Alkalinity (100 g/l, water)10.5 - 12.0
Proteinspasses test
Chloride (Cl)≤ 200 ppm
Sulfate (SO₄)≤ 200 ppm
Heavy metals (as Pb)≤ 10 ppm
As (Arsenic)≤ 1 ppm
Cu (Copper)*≤ 25 ppm
Fe (Iron)≤ 10 ppm
Mn (Manganese)≤ 25 ppm
Mo (Molybdenum)*≤ 2.5 ppm
Ni (Nickel)≤ 2 ppm
Zn (Zinc)≤ 130 ppm
Other amino acids (TLC)≤ 0.4 %
Related substances (TLC)passes test
Related Compounds, total (TLC)≤ 0.5 %
Ninhydrin-positive substances (LC) (any ninhydrin-positive impurity)≤ 0.2 %
Ninhydrin-positive substances (LC) (ammonium (570 nm))≤ 0.02 %
Ninhydrin-positive substances (LC) (total impurities)≤ 0.5 %
Residual solvents (ICH Q3C)excluded by manufacturing process
Sulfated ash (600 °C)≤ 0.1 %
Loss on drying (105 °C; 3 h)≤ 0.30 %
Bacterial endotoxins≤ 2.0 I.U./g
Bacterial endotoxins (ChP)< 10.0
Microbiological test (total aerobic microbial count (TAMC))≤ 10²
Microbiological test (total yeast and mould count (TYMC))≤ 10¹
Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
Corresponds to Ph. Eur., ChP, JP, USP.
Global Trade Item Number
Catalogue Number GTIN
1015870001 04027269365202
1015870101 04065269180449
1015871000 04022536901527
1015879010 04022536901534

Documentation

Material Qualification Dossier

TitleVersion
9.0

Quality Management Dossier (Open Access)

Title

Operational Excellence Dossier

Title

L-Arginine SDS

Title

Safety Data Sheet (SDS) 

L-Arginine Certificates of Analysis

Product Number PackagingSpecificationLot Number
1015870001 Plastic bottlePDF Specification Document
1015870101 Plastic bottlePDF Specification Document
1015871000 Plastic bottlePDF Specification Document
1015879010 Plastic drumPDF Specification Document

Certificates

Title