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420311 Kanamycin Sulfate, Streptomyces kanamyceticus - CAS 25389-94-0 - Calbiochem

An aminoglycoside antibiotic effective against Gram-positive and Gram-negative organisms.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Kamycin

Primary Target: protein biosynthesis
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
25389-94-0C₁₈H₃₆N₄O₁₁ · H₂SO₄
Description
OverviewContains more than 98% kanamycin A. An aminoglycoside antibiotic effective against Gram-positive and Gram-negative organisms. Inhibitor of protein biosynthesis that acts on the 30S ribosome, causing misreading of the genetic code. May cause renal damage and ototoxicity.
Potency: ≥750 µg/mg
Catalogue Number420311
Brand Family Calbiochem®
SynonymsKamycin
References
ReferencesLech, K., and Brent, R. 1995. in Current Protocols in Mol. Biol. Vol. 1 (Ausubel, F.M., et al., eds.) John Wiley & Sons, New York.
Kahn, R.W., et al. 1993. Proc. Natl. Acad. Sci. USA 90, 9295.
Cardon, G.H., et al. 1993. Plant J. 3, 773.
Maniatis, T., et al. 1989. In Molecular Cloning, A Laboratory Manual, Second Edition. Cold Spring Harbor, New York. p.1.6, A.6.
Korzybyski, T., et al. 1978. In Antibiotics, Origin, Nature, and Properties 1, 690.
Stiffler, P.W., et al. 1974. Antimicrob. Agents Chemother. 6, 516.
Umezawa, S., et al. 1968. J. Antibiot. 21, 367.
Product Information
CAS number25389-94-0
FormWhite to off-white solid
Hill FormulaC₁₈H₃₆N₄O₁₁ · H₂SO₄
Chemical formulaC₁₈H₃₆N₄O₁₁ · H₂SO₄
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary Targetprotein biosynthesis
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
RTECSNZ3225030
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Storage +15°C to +30°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, sterilize by filtration through a 0.22 µm pore-size filter, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
420311 0

Documentation

Kanamycin Sulfate, Streptomyces kanamyceticus - CAS 25389-94-0 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

Kanamycin Sulfate, Streptomyces kanamyceticus - CAS 25389-94-0 - Calbiochem Certificates of Analysis

TitleLot Number
420311

References

Reference overview
Lech, K., and Brent, R. 1995. in Current Protocols in Mol. Biol. Vol. 1 (Ausubel, F.M., et al., eds.) John Wiley & Sons, New York.
Kahn, R.W., et al. 1993. Proc. Natl. Acad. Sci. USA 90, 9295.
Cardon, G.H., et al. 1993. Plant J. 3, 773.
Maniatis, T., et al. 1989. In Molecular Cloning, A Laboratory Manual, Second Edition. Cold Spring Harbor, New York. p.1.6, A.6.
Korzybyski, T., et al. 1978. In Antibiotics, Origin, Nature, and Properties 1, 690.
Stiffler, P.W., et al. 1974. Antimicrob. Agents Chemother. 6, 516.
Umezawa, S., et al. 1968. J. Antibiot. 21, 367.

Brochure

Title
Antibiotics Profiler
Bulk Product Guide
Overnight Express Autoinduction Systems

Citations

Title
  • Thomas S. Lendvay, et al. (2007) Compensatory paracrine mechanisms that define the urothelial response to injury in partial bladder outlet obstruction. American Journal of Physiology: Renal 293, F1147-F1156.
    		•
    Data Sheet

    Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

    Revision24-September-2010 JSW
    SynonymsKamycin
    DescriptionContains more than 98% kanamycin A. An aminoglycoside antibiotic affective against gram-positive and gram-negative organisms. Inhibitor of protein biosynthesis that acts on the 70S ribosome, causing misreading of the genetic code. May cause renal damage and ototoxicity.
    FormWhite to off-white solid
    CAS number25389-94-0
    RTECSNZ3225030
    Chemical formulaC₁₈H₃₆N₄O₁₁ · H₂SO₄
    Structure formulaStructure formula
    SolubilityH₂O (10 mg/ml)
    Storage +15°C to +30°C
    Do Not Freeze Ok to freeze
    Special InstructionsFollowing reconstitution, sterilize by filtration through a 0.22 µm pore-size filter, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
    Merck USA index14, 5281
    ReferencesLech, K., and Brent, R. 1995. in Current Protocols in Mol. Biol. Vol. 1 (Ausubel, F.M., et al., eds.) John Wiley & Sons, New York.
    Kahn, R.W., et al. 1993. Proc. Natl. Acad. Sci. USA 90, 9295.
    Cardon, G.H., et al. 1993. Plant J. 3, 773.
    Maniatis, T., et al. 1989. In Molecular Cloning, A Laboratory Manual, Second Edition. Cold Spring Harbor, New York. p.1.6, A.6.
    Korzybyski, T., et al. 1978. In Antibiotics, Origin, Nature, and Properties 1, 690.
    Stiffler, P.W., et al. 1974. Antimicrob. Agents Chemother. 6, 516.
    Umezawa, S., et al. 1968. J. Antibiot. 21, 367.
    Citation
  • Thomas S. Lendvay, et al. (2007) Compensatory paracrine mechanisms that define the urothelial response to injury in partial bladder outlet obstruction. American Journal of Physiology: Renal 293, F1147-F1156.
    		•