Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

124017 InSolution™ Akt Inhibitor VIII, Isozyme-Selective, Akti-1/2 - Calbiochem

Overview

Key Spec Table

Empirical Formula
C₃₄H₂₉N₇O

Products

Catalogue NumberPackaging Qty/Pack
124017-1MG Plastic ampoule 1 mg
Description
Catalogue Number124017
Brand Family Calbiochem®
References
ReferencesBarnett, S.F., et al. 2005. Biochem. J. 385, 399.
DeFeo-Jones, D., et al. 2005. Mol. Cancer Ther. 4, 271.
Zhao, Z., et al. 2005. Bioorg. Med. Chem. Lett. 15, 905.
Lindsley, C.W., et al. 2005. Bioorg. Med. Chem. Lett. 15, 761.
Product Information
ATP CompetitiveN
FormLiquid
FormulationA 10 mM (1 mg/181 µl) solution of Akt Inhibitor VIII, Isozyme-Selective, Akti-1/2 (Cat. No. 124018) in DMSO.
Hill FormulaC₃₄H₂₉N₇O
Chemical formulaC₃₄H₂₉N₇O
Hygroscopic Hygroscopic
ReversibleY
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
ApplicationInSolution Akt Inhibitor VIII, Isozyme-Selective, Akti-1/2, CAS 612847-09-3, is a 10 mM solution in DMSO. A cell-permeable, reversible, selective inhibitor of Akt1 & Akt2 (IC50 = 58 nM & 210 nM).
Biological Information
Primary TargetAkt1, Akt2, Akt3
Primary Target IC<sub>50</sub>58 nM, 210 nM, and 2.12 µM for Akt1, Akt2, and Akt3, respectively, in in vitro kinase assays
Purity≥95% by HPLC
Concentration Label Please refer to vial label for lot-specific concentration
Physicochemical Information
Cell permeableY
Storage and Shipping Information
Ship Code Dry Ice Only
Toxicity Irritant
Storage ≤ -70°C
Protect from Light Protect from light
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
Packaging Information
Packaged under inert gas Packaged under inert gas
Global Trade Item Number
Catalogue Number GTIN
124017-1MG 07790788047993