Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

GF336 IL-33,
Human Recombinant Animal Free

IL-33,
Human Recombinant Animal Free MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
UniProt Number: O95760
View Products on Sigmaaldrich.com
GF336
10µg  
Purchase on Sigma-Aldrich

Overview

Key Spec Table

SourcePurity
Protein is expressed in E.coli.
The protein is manufactured without the use of any animal products/reagents and is considered Animal-Free and can be used in protocols where possible transmisson of animal viruses and contamination must be avoided.		Product endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
Description
Catalogue NumberGF336
DescriptionIL-33,
Human Recombinant Animal Free
Alternate Names
  • Interleukin-33
  • IL33
Background InformationHuman IL-33 is a proinflammatory protein that shares structural and functional characteristics with the IL-1 cytokine family. It binds and signals through the IL-1RL1/ST2 receptor activating NF-kappaB and MAP kinases. IL-33 induces production of TH2 cell related cytokines, including IL-4, IL-5 and IL-13, and exerts multiple inflammation related bioactivities.
Recombinant human IL-33 is a 17.9 kDa protein containing 159 amino acid residues.
Product Information
PresentationProduct is presented in 10 mM Sodium Phosphate, pH 8.0 + 0.5 mM DTT and is filtered through a 0.2 micron filter before lyophilization.
Quality LevelMQ100
Biological Information
PurityProduct endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
SourceProtein is expressed in E.coli.
The protein is manufactured without the use of any animal products/reagents and is considered Animal-Free and can be used in protocols where possible transmisson of animal viruses and contamination must be avoided.
UniProt Number
Product Usage Statements
Quality AssuranceDetermined by its ability to stimulate the proliferation of mouse D10S cells. The expected ED50 is ≤ 0.05 ng/ml, corresponding to a specific activity of ≥2 x 10^7 units/mg.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStore at -20°C for up to 4 months from date of receipt Centrifuge the vial prior to opening.
Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein and store in working aliquots at -20°C.
Packaging Information
Material Size10µg
Global Trade Item Number
Catalogue Number GTIN
GF336 04053252979378