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GF326 IL-13,
Human Recombinant Animal Free

IL-13,
Human Recombinant Animal Free MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
UniProt Number: P35225
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GF326
10µg  
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Overview

Replacement Information

Key Spec Table

SourcePurity
Protein is expressed in E.coli.
The protein is manufactured without the use of any animal products/reagents and is considered Animal-Free and can be used in protocols where possible transmisson of animal viruses and contamination must be avoided.		Product endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
Description
Catalogue NumberGF326
DescriptionIL-13,
Human Recombinant Animal Free
Alternate Names
  • Interleukin-13
  • IL13
Background InformationIL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and also by mast cells and NK cells. Targeted deletion of IL-13 in mice resulted in impaired Th2 cell development and indicated an important role for IL-13 in the expulsion of gastrointestinal parasites. IL-13 exerts anti-inflammatory effects on monocytes and macrophages and it inhibits the expression of inflammatory cytokines such as IL-1β, TNF-α, IL-6 and IL-8. IL-13 has also been shown to enhance B cell proliferation and to induce isotype switching resulting in increased production of IgE. Blocking of IL-13 activity inhibits the pathophysiology of asthma. Human and murine IL-13 is cross-species reactive.
Recombinant human IL-13 is a 12.6 kDa protein consisting of 115 amino acid residues.
References
Product Information
PresentationProduct is presented in 20 mM Sodium Phosphate, pH 7.0 and is filtered through a 0.2 micron filter before lyophilization.
Quality LevelMQ100
Applications
Biological Information
PurityProduct endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
SourceProtein is expressed in E.coli.
The protein is manufactured without the use of any animal products/reagents and is considered Animal-Free and can be used in protocols where possible transmisson of animal viruses and contamination must be avoided.
UniProt Number
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceThe ED50 was determined by its ability to stimulate the proliferation of human TF-1 cells. The expected ED50 is ≤ 1.0 ng/ml, corresponding to a specific activity of ≥1 x 10^6
units/mg.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStore at -20°C for up to 4 months from date of receipt Centrifuge the vial prior to opening.
Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein and store in working aliquots at -20°C.
Packaging Information
Material Size10µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
GF326 04053252978890

Documentation

IL-13,
Human Recombinant Animal Free SDS

Title

Safety Data Sheet (SDS) 

IL-13,
Human Recombinant Animal Free Certificates of Analysis

TitleLot Number
IL-13 2842870
IL-13, Human Recombinant Animal Free - Q2442276 Q2442276
IL-13, Human Recombinant Animal Free 2478461
IL-13, Human Recombinant Animal Free - 3179184 3179184
IL-13, Human Recombinant Animal Free - 3321812 3321812
IL-13, Human Recombinant Animal Free - 3775368 3775368
IL-13, Human Recombinant Animal Free - 3883569 3883569
IL-13, Human Recombinant Animal Free - 3927580 3927580
IL-13, Human Recombinant Animal Free - 4007639 4007639
IL-13, Human Recombinant Animal Free - 4058966 4058966
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