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368068 Granzyme B Substrate IX, Fluorogenic

Granzyme B Substrate IX, Fluorogenic MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Ac-IEPD-AMC

368068
  
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Overview

Replacement Information
Description
Overview

This product has been discontinued.





A fluorogenic substrate for granzyme B (kcat/Km = 3,330 M-1s-1) that also recognizes granzyme B variants (kcat/Km = 55 M-1s-1 for R192A and kcat/Km = 8.8 M-1s-1 for R192E).
Catalogue Number368068
Brand Family Calbiochem®
SynonymsAc-IEPD-AMC
References
ReferencesHarris, J.L., et al. 1998. J. Biol. Chem. 273, 27364.
Thornberry, N.A., et al. 1997. J. Biol. Chem. 272, 17907.
Product Information
FormLyophilized
Hill FormulaC₃₂H₄₁N₅O₁₁
Chemical formulaC₃₂H₄₁N₅O₁₁
Applications
Biological Information
Purity≥95% by HPLC
Physicochemical Information
Emission max.
Excitation max.
Peptide SequenceAc-Ile-Glu-Pro-Asp-AMC
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
368068 0

Documentation

Granzyme B Substrate IX, Fluorogenic Certificates of Analysis

TitleLot Number
368068

References

Reference overview
Harris, J.L., et al. 1998. J. Biol. Chem. 273, 27364.
Thornberry, N.A., et al. 1997. J. Biol. Chem. 272, 17907.

Brochure

Title
Caspases and other Apoptosis Related Tools Brochure
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision07-July-2008 RFH
SynonymsAc-IEPD-AMC
DescriptionA fluorogenic substrate for granzyme B (kcat/Km = 3,330 M-1s-1) that also recognizes granzyme B variants (kcat/Km = 55 M-1s-1 for R192A and kcat/Km = 8.8 M-1s-1 for R192E).
FormLyophilized
Intert gas (Yes/No) Packaged under inert gas
Chemical formulaC₃₂H₄₁N₅O₁₁
Peptide SequenceAc-Ile-Glu-Pro-Asp-AMC
Purity≥95% by HPLC
SolubilityDMSO (5 mg/ml)
Storage Protect from light
-20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesHarris, J.L., et al. 1998. J. Biol. Chem. 273, 27364.
Thornberry, N.A., et al. 1997. J. Biol. Chem. 272, 17907.