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362338 Glyco-SNAP-1 - Calbiochem

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362338
  
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Overview

Replacement Information

Key Spec Table

Empirical Formula
C₁₃H₂₃N₃O₈S
Description
Overview

This product has been discontinued.



A water-soluble nitric oxide (NO) donor. More stable (t½ = 28.5-30.2 hr) than SNAP (Cat. No. 487910) in aqueous solution with or without EDTA and is relatively stable at high pH (pH 8 - 9). The SNAP moiety acts as an NO group donor and the sugar moiety provides hydrophilicity and specificity. Compared to SNAP, glyco-SNAP-1 decomposes at a much slower rate in the presence of thiols such as cysteine or glutathione.

Catalogue Number362338
Brand Family Calbiochem®
SynonymsN-(β-D-Glucopyranosyl)-N²-acetyl-S-nitroso-D,L-penicillaminamide
References
ReferencesHou, Y., et al. 1999. Methods Enzymol. 301, 242.
Ramirez, J., et al. 1996. Bioorg. Med. Chem. Lett. 6, 2575.
Product Information
ATP CompetitiveN
FormGreen crystalline solid
Hill FormulaC₁₃H₂₃N₃O₈S
Chemical formulaC₁₃H₂₃N₃O₈S
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetA water-soluble nitric oxide (NO) donor
Purity≥96% by NMR
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsUnstable in solution; reconstitute just prior to use.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
362338 0

Documentation

Glyco-SNAP-1 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

Glyco-SNAP-1 - Calbiochem Certificates of Analysis

TitleLot Number
362338

References

Reference overview
Hou, Y., et al. 1999. Methods Enzymol. 301, 242.
Ramirez, J., et al. 1996. Bioorg. Med. Chem. Lett. 6, 2575.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision02-July-2008 RFH
SynonymsN-(β-D-Glucopyranosyl)-N²-acetyl-S-nitroso-D,L-penicillaminamide
DescriptionA water-soluble and stable nitric oxide (NO) donor (t½ = 28.5-30.2 hr). Glyco-SNAP-1 is more stable than SNAP (Cat. No. 487910) in aqueous solution with or without EDTA and is relatively stable at high pH (pH 8-9). The SNAP moiety acts as an NO group donor and the sugar fragment provides hydrophilicity and specificity. Compared to SNAP, glyco-SNAP-1 decomposes much more slowly in the presence of thiols such as cysteine or glutathione.
FormGreen crystalline solid
Chemical formulaC₁₃H₂₃N₃O₈S
Structure formulaStructure formula
Purity≥96% by NMR
SolubilityH₂O (100 mg/ml), Aqueous Buffers (100 mg/ml), Methanol (5 mg/ml)
Storage Protect from light
-20°C
Do Not Freeze Ok to freeze
Special InstructionsUnstable in solution; reconstitute just prior to use.
Toxicity Standard Handling
ReferencesHou, Y., et al. 1999. Methods Enzymol. 301, 242.
Ramirez, J., et al. 1996. Bioorg. Med. Chem. Lett. 6, 2575.