Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

14-605 Fer Protein, active, 10 µg

14-605
10 µg  
Purchase on Sigma-Aldrich

Overview

Replacement Information
Description
Catalogue Number14-605
Brand Family Upstate
Trade Name
  • Upstate
DescriptionFer Protein, active, 10 µg
OverviewN-terminal His6 tagged, recombinant human Fer amino acids 541-end
References
Product Information
Quality LevelMQ100
Applications
ApplicationActive, N-terminal His6 tagged, recombinant human Fer amino acids 541-end, for use in Kinase Assays.
Key Applications
  • Kinase Assay
Biological Information
Sourceexpressed by baculovirus in Sf21 insect cells
Specific ActivityFor Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme
Entrez Gene Number
Entrez Gene SummaryFer protein is a member of the FPS/FES family of nontransmembrane receptor tyrosine kinases. It regulates cell-cell adhesion and mediates signaling from the cell surface to the cytoskeleton via growth factor receptors.
Gene Symbol
  • FER
  • p94-FER
  • TYK3
Protein TargetFer
Purification MethodNi2+/NTA-agarose
Target Sub-FamilyTK
UniProt Number
UniProt SummaryFUNCTION: SwissProt: P16591 # Tyrosine kinase of the non-receptor type. Probably performs an important function, perhaps in regulatory processes such as cell cycle control.
SIZE: 822 amino acids; 94638 Da
SUBCELLULAR LOCATION: Cytoplasm. Nucleus. Note=Associated with the chromatin.
TISSUE SPECIFICITY: Expressed in a variety of lymphoid cell lines.
SIMILARITY: SwissProt: P16591 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. & Contains 1 FCH domain. & Contains 1 protein kinase domain. & Contains 1 SH2 domain.
Molecular Weight35.6kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality Assuranceroutinely evaluated by phosphorylation of IGF-IRtide (Catalog #12-527)
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions6 months at -70°C
Packaging Information
Material Size10 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
14-605 04053252272622