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309795 DIDS, Disodium Salt - CAS 53005-05-3 - Calbiochem

Overview

Key Spec Table

CAS #Empirical Formula
53005-05-3C₁₆H₈N₂O₆S₄ · 2Na

Products

Catalogue NumberPackaging Qty/Pack
309795-250MG Plastic ampoule 250 mg
Description
OverviewBinds covalently and irreversibly to the outer surface of human erythrocyte membranes. Inhibits ATP transport into endoplasmic reticulum vesicles. Anion transport inhibitor that inhibits Cl uptake (IC50 = 150 nM) in neuroblastoma cells. Has anti-ulcerous properties.
Catalogue Number309795
Brand Family Calbiochem®
Synonyms4,4ʹ-Diisothiocyanostilbene-2,2ʹ-disulfonic Acid, 2Na
References
ReferencesBettendorff, L., et al. 1995. Biochem. Biophys. Res. Commun. 207, 375.
Horie, S., et al. 1993. Res. Commun. Chem. Pathol. Pharmacol. 79, 117.
Mayinger, P., and Meyer, D.I. 1993. EMBO J. 12, 659.
Catantchik, Z.I., and Rothstein, A. 1974. J. Membr. Biol. 15, 207.
Product Information
CAS number53005-05-3
ATP CompetitiveN
FormYellow solid
Hill FormulaC₁₆H₈N₂O₆S₄ · 2Na
Chemical formulaC₁₆H₈N₂O₆S₄ · 2Na
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Biological Information
Primary TargetCl- uptake
Primary Target IC<sub>50</sub>150 nM inhibiting Cl- uptake in neuroblastoma cells
Purity≥85% by HPLC
Physicochemical Information
Cell permeableN
Safety Information
R PhraseR: 36/37/38

Irritating to eyes, respiratory system and skin.
S PhraseS: 26-36

In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing.
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Irritant
Storage -20°C
Protect from Light Protect from light
Protect from Moisture Protect from moisture
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.
Global Trade Item Number
Catalogue Number GTIN
309795-250MG 04055977216790