Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

216201 Carboxyatractyloside, Potassium Salt, Xanthium sibiricum - CAS 35988-42-2 - Calbiochem

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: C-ATR, CAT

View Products on Sigmaaldrich.com
216201
  
Purchase on Sigma-Aldrich

Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
35988-42-2C₃₁H₄₃O₁₈S₂K₃•3H₂O
Description
Overview

This product has been discontinued.



We are offering Carboxyatractyloside potassium salt (Cat. No. C4992) as a possible alternative. Please read the alternative product documentation carefully and contact technical service if you need additional information.






Toxic compound isolated from the plant Xanthium sibiricum. A highly selective and potent inhibitor of adenine nucleotide translocator (ANT) (Ki < 10 nM) and inducer of permeability transition pore opening. Stabilizes the nucleoside binding site of ANT on the cytoplasmic side of the inner membrane and blocks the exchange of matrix ATP and cytoplasmic ADP. Does not affect the activity of mitochondrial multiple conductance channel (MCC).
CAS No. refers to that of the free acid.
Catalogue Number216201
Brand Family Calbiochem®
SynonymsC-ATR, CAT
References
ReferencesPebay-Peyroula, E., et al. 2003. Nature 426, 39.
Huber, T., et al. 1999. Biochemistry 38, 762.
Fiore, C., et al. 1998. Biochimie 80, 137.
Lohret, T.A., et al. 1996. J. Biol. Chem. 271, 4846.
Product Information
CAS number35988-42-2
FormWhite solid
Hill FormulaC₃₁H₄₃O₁₈S₂K₃•3H₂O
Chemical formulaC₃₁H₄₃O₁₈S₂K₃•3H₂O
Hygroscopic Hygroscopic
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Purity≥95% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
R PhraseR: 23/24/25

Toxic by inhalation, in contact with skin and if swallowed.
S PhraseS: 36/37-45

Wear suitable protective clothing and gloves.
In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Toxic
Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Storage -20°C
Protect from Moisture Protect from moisture
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
216201 0

Documentation

Carboxyatractyloside, Potassium Salt, Xanthium sibiricum - CAS 35988-42-2 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

Carboxyatractyloside, Potassium Salt, Xanthium sibiricum - CAS 35988-42-2 - Calbiochem Certificates of Analysis

TitleLot Number
216201

References

Reference overview
Pebay-Peyroula, E., et al. 2003. Nature 426, 39.
Huber, T., et al. 1999. Biochemistry 38, 762.
Fiore, C., et al. 1998. Biochimie 80, 137.
Lohret, T.A., et al. 1996. J. Biol. Chem. 271, 4846.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision27-November-2008 RFH
SynonymsC-ATR, CAT
DescriptionToxic compound isolated from the plant Xanthium sibiricum. A highly selective and potent inhibitor of adenine nucleotide translocator (ANT) (Ki <10 nM) and inducer of permeability transition pore opening. Stabilizes the nucleoside binding site of ANT on the cytoplasmic side of the inner membrane and blocks the exchange of matrix ATP and cytoplasmic ADP. Does not affect the activity of mitochondrial multiple conductance channel (MCC). CAS No. refers to that of the free acid.
FormWhite solid
CAS number35988-42-2
Chemical formulaC₃₁H₄₃O₁₈S₂K₃•3H₂O
Structure formulaStructure formula
Purity≥95% by HPLC
SolubilityH₂O (10 mg/ml)
Storage Protect from moisture
-20°C
Hygroscopic
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Toxic
ReferencesPebay-Peyroula, E., et al. 2003. Nature 426, 39.
Huber, T., et al. 1999. Biochemistry 38, 762.
Fiore, C., et al. 1998. Biochimie 80, 137.
Lohret, T.A., et al. 1996. J. Biol. Chem. 271, 4846.