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GF302 BMP-4 Protein, Human Recombinant Animal Free

Bone morphogenetic protein 4 (BMP4) is a TGFβ superfamily lig& that is widely expressed from early embryogenesis through adulthood. The Recombinant animal free human BMP-4 protein is manufactured

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BMP-4 Protein, Human Recombinant Animal Free MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
UniProt Number: P12644 Entrez Gene Number: NM_001202.3, NM_130850.2, NM_130851.2
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GF302
10 µg  
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Overview

Key Spec Table

SourcePurity
E. coli Product is endotoxin free (< 0.1ng/μg of protein (<1EU/μg) and greater than 98% pure by SDS-PAGE gel and HPLC analyses
Description
Catalogue NumberGF302
DescriptionBMP-4 Protein, Human Recombinant Animal Free
Alternate Names
  • BMP4
  • Bone morphogentic protein-4
  • DVR-4
Background InformationBone morphogentic protein 4 (BMP4) is a TGFβ superfamily ligand that is widely expressed from early embryogenesis through adulthood. It plays an important role in mesenchyme formation, epidermal determination, suppression of neural induction, the development of multiple organs, and tissue repair. Like BMP-7, BMP-4 is involved in the development and maintenance of bone and cartilage. Reduced expression of BMP-4 is associated with a number of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva.
Animal free human recombinant BMP4 is a fully active homodimeric protein consisting of two 107 amino acid subunits which correspond to amino acids 303-408 of the full length BMP-4 precursor.
Product Information
Formulation
PresentationProduct is filtered through a 0.2 micron filter before lyophilization.
Quality LevelMQ100
Applications
ApplicationBone morphogenetic protein 4 (BMP4) is a TGFβ superfamily lig& that is widely expressed from early embryogenesis through adulthood. The Recombinant animal free human BMP-4 protein is manufactured using all non-animal reagents.
Biological Information
PurityProduct is endotoxin free (< 0.1ng/μg of protein (<1EU/μg) and greater than 98% pure by SDS-PAGE gel and HPLC analyses
SourceE. coli
Cross ReactivityMouse
Entrez Gene Number
UniProt Number
Product Usage Statements
Quality AssuranceBioactivity assay: Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 for this effect is 5-10 ng/ml.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStore at -20°C for up to 6 months from date of receipt.
Packaging Information
Material Size10 µg
Global Trade Item Number
Catalogue Number GTIN
GF302 04053252691430