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181198 Arachidonic Acid - CAS 506-32-1 - Calbiochem

Precursor for prostaglandins, prostacyclin, and thromboxane.

Arachidonic Acid - CAS 506-32-1 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: cis,cis,cis,cis-5,8,11,14-Eicosatetraenoic Acid, 20:4

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181198
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
506-32-1C₂₀H₃₂O₂

Products

Catalogue NumberPackaging Qty/Pack
181198-100MG Glass bottle 100 mg
181198-1GM Plastic ampoule 1 gm
Description
OverviewPrecursor for prostaglandins, prostacyclin, and thromboxane. Binds to G-protein α-subunits in a covalent, post-translational manner. Inhibits Ras-GAP. Stimulates the synthesis of nitric oxide by platelets. Modulates nitric oxide production by prostaglandin synthesis via the cyclooxygenase pathway.
Catalogue Number181198
Brand Family Calbiochem®
Synonymscis,cis,cis,cis-5,8,11,14-Eicosatetraenoic Acid, 20:4
References
ReferencesHallak, H., et al. 1994. J. Biol. Chem. 269, 4713.
Khurana, G., and Bennett, M.R. 1993. Br. J. Pharmacol. 109, 480.
Han, J.-W., et al. 1991. Science 252, 576.
Radomski, M.W., et al. 1990. Br. J. Pharmacol. 101, 325.
Neddleman P., et al. 1986. Annu. Rev. Biochem. 55, 69.
Product Information
CAS number506-32-1
ATP CompetitiveN
FormColorless oil
Hill FormulaC₂₀H₃₂O₂
Chemical formulaC₂₀H₃₂O₂
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetRas-GAP
Purity≥99% by TLC and GC
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
RTECSCE6675000
Safety Information
R PhraseR: 20/21/22-36/37/38

Harmful by inhalation, in contact with skin and if swallowed.
Irritating to eyes, respiratory system and skin.
S PhraseS: 36-26

Wear suitable protective clothing.
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Product Usage Statements
Storage and Shipping Information
Ship Code Dry Ice Only
Toxicity Harmful
Storage ≤ -70°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
181198-100MG 04055977205008
181198-1GM 04055977204995

Documentation

Arachidonic Acid - CAS 506-32-1 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

Arachidonic Acid - CAS 506-32-1 - Calbiochem Certificates of Analysis

TitleLot Number
181198

References

Reference overview
Hallak, H., et al. 1994. J. Biol. Chem. 269, 4713.
Khurana, G., and Bennett, M.R. 1993. Br. J. Pharmacol. 109, 480.
Han, J.-W., et al. 1991. Science 252, 576.
Radomski, M.W., et al. 1990. Br. J. Pharmacol. 101, 325.
Neddleman P., et al. 1986. Annu. Rev. Biochem. 55, 69.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision15-April-2008 RFH
Synonymscis,cis,cis,cis-5,8,11,14-Eicosatetraenoic Acid, 20:4
DescriptionA cis-polyunsaturated fatty acid found in the plasma membrane. Major component of membrane phospholipids. Following its release by cellular phospholipases, it is enzymatically converted to a variety of inflammatory and vasoactive metabolites, such as prostaglandins (via the cyclooxygenase pathway), leukotrienes (via the lipoxygenase pathway), and epoxides (via the cytochrome P450 pathway). Binds to G-protein α-subunits in a covalent, posttranslational manner. Inhibits Ras-GAP. Stimulates the synthesis of nitric oxide by platelets.
FormColorless oil
Intert gas (Yes/No) Packaged under inert gas
CAS number506-32-1
RTECSCE6675000
Chemical formulaC₂₀H₃₂O₂
Structure formulaStructure formula
Purity≥99% by TLC and GC
SolubilityEthanol (5 mg/ml)
Storage Protect from light
≤ -70°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
Toxicity Harmful
Merck USA index14, 765
ReferencesHallak, H., et al. 1994. J. Biol. Chem. 269, 4713.
Khurana, G., and Bennett, M.R. 1993. Br. J. Pharmacol. 109, 480.
Han, J.-W., et al. 1991. Science 252, 576.
Radomski, M.W., et al. 1990. Br. J. Pharmacol. 101, 325.
Neddleman P., et al. 1986. Annu. Rev. Biochem. 55, 69.