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582005 Anti-Telomerase (Ab-2) Rabbit pAb

This Anti-Telomerase (Ab-2) Rabbit pAb is validated for use in Frozen Sections, Immunoblotting, Immunprecipitation, Paraffin Sections for the detection of Telomerase (Ab-2).

Anti-Telomerase (Ab-2) Rabbit pAb MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Anti-TERT

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Overview

Replacement Information

Key Spec Table

Species ReactivityHostAntibody Type
H, MRbPolyclonal Antibody
Description
Overview

This product has been discontinued.



Recognizes the ~125 kDa telomerase (TERT) protein.<.p>
Catalogue Number582005
Brand Family Calbiochem®
SynonymsAnti-TERT
References
ReferencesFu, W., et al. 2000. J. Mol. Neurosci. 14, 3.
Kharbanda, S., et al. 2000. Curr. Biol. 10, 568.
Vaziri, H., et al. 1999. Mol. Cell. Biol. 19, 2373.
Product Information
FormLiquid
FormulationUndiluted serum.
PreservativeNone
Quality LevelMQ100
Applications
Key Applications Frozen Sections
Immunoblotting (Western Blotting)
Immunoprecipitation
Paraffin Sections
Application NotesFrozen Sections (1:250-1:1000)
Immunoblotting (1:100)
Immunprecipitation (1:40)
Paraffin Sections (1:250-1:1000)
Application CommentsVariables associated with assay conditions will dictate the optimal working dilution.
Biological Information
Immunogena synthetic peptide corresponding to amino acids from an internal region of the catalytic subunit of human telomerase reverse transcriptase (hTERT)
ImmunogenHuman
HostRabbit
IsotypeIgG
Species Reactivity
  • Human
  • Mouse
Antibody TypePolyclonal Antibody
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Dry Ice Only
Toxicity Standard Handling
Storage -20°C
Avoid freeze/thaw Avoid freeze/thaw
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
582005 0

Documentation

Anti-Telomerase (Ab-2) Rabbit pAb SDS

Title

Safety Data Sheet (SDS) 

Anti-Telomerase (Ab-2) Rabbit pAb Certificates of Analysis

TitleLot Number
582005

References

Reference overview
Fu, W., et al. 2000. J. Mol. Neurosci. 14, 3.
Kharbanda, S., et al. 2000. Curr. Biol. 10, 568.
Vaziri, H., et al. 1999. Mol. Cell. Biol. 19, 2373.

Brochure

Title
Caspases and other Apoptosis Related Tools Brochure
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision16-August-2007 RFH
SynonymsAnti-TERT
ApplicationFrozen Sections (1:250-1:1000)
Immunoblotting (1:100)
Immunprecipitation (1:40)
Paraffin Sections (1:250-1:1000)
DescriptionRabbit polyclonal antibody supplied as undiluted serum. Recognizes the ~125 kDa telomerase (TERT) protein.
BackgroundThe 3' ends of chromosomes are capped with telomere sequences (TTAGGG; 6-26 nucleotides in length) by ribonucleo-protein telomerase during DNA replication. Telomerase is an unusual RNA-dependent DNA polymerase that uses an RNA component to specify the addition of telomere. In ciliated protozoa and yeast, telomere length is maintained by regulating the activity of telomerase. Many mammalian cells do not express telomerase, resulting into shortening of the telomere with each cell division, ultimately causing chromosomal instability, aging and cell death. ~4.8 kb of telomeric DNA is lost with each cell division. Most recently, introduction of telomerase into normal human cells has been shown to extend normal cell life by ~20 doublings.
HostRabbit
Immunogen speciesHuman
Immunogena synthetic peptide corresponding to amino acids from an internal region of the catalytic subunit of human telomerase reverse transcriptase (hTERT)
IsotypeIgG
Specieshuman, mouse
FormLiquid
FormulationUndiluted serum.
PreservativeNone
CommentsVariables associated with assay conditions will dictate the optimal working dilution.
Storage Avoid freeze/thaw
-20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
Toxicity Standard Handling
ReferencesFu, W., et al. 2000. J. Mol. Neurosci. 14, 3.
Kharbanda, S., et al. 2000. Curr. Biol. 10, 568.
Vaziri, H., et al. 1999. Mol. Cell. Biol. 19, 2373.