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565953 Anti-Sialyl Lewis x Mouse mAb (KM93)

This Anti-Sialyl Lewis x Mouse mAb (KM93) is validated for use in Flow Cytometry, Adhesion Blockade, Paraffin Sections for the detection of Sialyl Lewis x.

Anti-Sialyl Lewis x Mouse mAb (KM93) MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Anti-Sialyl Lex

565953
  
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Overview

Replacement Information

Key Spec Table

Host
M
Description
Overview

This product has been discontinued.





Recognizes the SLex carbohydrate epitope on glycoproteins and glycolipids on adenocarcinomas in lung primary tumors and with a variety of tumor cell lines.
Catalogue Number565953
Brand Family Calbiochem®
SynonymsAnti-Sialyl Lex
References
ReferencesNagata, K., et al. 1994. J. Biol. Chem. 269, 23290.
Sasaki, K., et al. 1993. J. Biol. Chem. 268, 22782.
Product Information
FormLiquid
FormulationIn PBS, 1% BSA, pH 7.2.
Preservative≤0.1% sodium azide
Applications
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Flow Cytometry
Paraffin Sections
Application NotesFlow Cytometry (10 µg/ml)
Adhesion Blockade (10-100 µg/ml)
Paraffin Sections (1:40)
Application CommentsReacts with various cancerous tissue, including adenocarcinomas, cholangioma, and cancers of the stomach, colon, pancreas, breast, cervix, ovary mucinic cystic gland, and squamous cell epithelia. Reacts with various normal adult tissues, including stomach, colon, bronchus, pancreatic acinar cells, germ cells, some myeloid cells, and epithelia of the lung, pancreatic duct, gall duct, and renal tubule. Variables associated with assay conditions will dictate the proper working dilution.
Biological Information
Immunogenhuman lung adenocarcinoma cells
ImmunogenHuman
CloneKM93
HostMouse
IsotypeIgM
Concentration Label Please refer to vial label for lot-specific concentration
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Blue Ice Only
Toxicity Standard Handling
Storage -20°C
Avoid freeze/thaw Avoid freeze/thaw
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
565953 0

Documentation

Anti-Sialyl Lewis x Mouse mAb (KM93) SDS

Title

Safety Data Sheet (SDS) 

Anti-Sialyl Lewis x Mouse mAb (KM93) Certificates of Analysis

TitleLot Number
565953

References

Reference overview
Nagata, K., et al. 1994. J. Biol. Chem. 269, 23290.
Sasaki, K., et al. 1993. J. Biol. Chem. 268, 22782.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision15-August-2007 RFH
SynonymsAnti-Sialyl Lex
ApplicationFlow Cytometry (10 µg/ml)
Adhesion Blockade (10-100 µg/ml)
Paraffin Sections (1:40)
DescriptionPurified mouse monoclonal antibody. Recognizes the Sialyl Lewis x epitope on glycoproteins and glycolipids.
BackgroundSialyl Lewis x [SLex; NeuAcα2,3Galβ1,4(Fucα1,3)GlcNAc] is a tetrasaccharide that acts as a minimal ligand (Kd = 129 µM) for E-selectin (ELAM; endothelial leukocyte adhesion molecule), an endothelial cell-surface glycoprotein that mediates recruitment of neutrophils and monocytes to sites of endothelial inflammation.
HostMouse
Immunogen speciesHuman
Immunogenhuman lung adenocarcinoma cells
CloneKM93
IsotypeIgM
Specieshuman
FormLiquid
FormulationIn PBS, 1% BSA, pH 7.2.
Concentration Label Please refer to vial label for lot-specific concentration
Preservative≤0.1% sodium azide
CommentsReacts with various cancerous tissue, including adenocarcinomas, cholangioma, and cancers of the stomach, colon, pancreas, breast, cervix, ovary mucinic cystic gland, and squamous cell epithelia. Reacts with various normal adult tissues, including stomach, colon, bronchus, pancreatic acinar cells, germ cells, some myeloid cells, and epithelia of the lung, pancreatic duct, gall duct, and renal tubule. Variables associated with assay conditions will dictate the proper working dilution.
Storage Avoid freeze/thaw
-20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
Toxicity Standard Handling
ReferencesNagata, K., et al. 1994. J. Biol. Chem. 269, 23290.
Sasaki, K., et al. 1993. J. Biol. Chem. 268, 22782.