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MABC550 Anti-Pex3 Antibody, clone 14F3.2

MABC550
100 µg  
Purchase on Sigma-Aldrich

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Overview

Replacement Information

Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWB, IHCMPurifiedMonoclonal Antibody
Description
Catalogue NumberMABC550
DescriptionAnti-Pex3 Antibody, clone 14F3.2
Alternate Names
  • Pex3
  • Peroxisomal biogenesis factor 3
  • Peroxin-3
  • Peroxisomal assembly protein PEX3
Background InformationPex3 (also known as peroxin-3, peroxisomal assembly protein PEX3, peroxisomal biogenesis factor 3, transformation-related protein 18) is a multitransmembrane peroxisome protein that is encoded by the PEX3 gene in human (also known as PBD10A and TRG18). Pex19 is involved in maintaining peroxisome biosynthesis and integrity by acting as a docking factor for pex19 and, together with other peroxins (PEXs), is essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs), including Zellweger syndrome (ZWS), neonatal adrenoleukodystrophy (NALD), infantile Refsum disease (IRD), and classical rhizomelic chondrodysplasia punctata (RCDP), are lethal diseases characterized by multiple defects in peroxisome function, resulting in failure of importing one or more classes of peroxisomal matrix proteins into the organelle.
References
Product Information
FormatPurified
PresentationPurified mouse monoclonal IgG2bκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ300
Applications
ApplicationAnti-Pex3 Antibody, clone 14F3.2 is an antibody against Pex3 for use in Western Blotting and Immunohistochemistry.
Key Applications
  • Western Blotting
  • Immunohistochemistry
Application NotesImmunohistochemistry Analysis: A 1:50-1,000 dilution from a representative lot detected Pex3 in human liver and human kidney tissue.
Biological Information
ImmunogenGST-tagged recombinant protein corresponding to human Pex3.
Clone14F3.2
ConcentrationPlease refer to lot specific datasheet.
HostMouse
IsotypeIgG2bκ
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • PEX3
Purification MethodProtein G Purified
UniProt Number
Molecular Weight~40 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in HepG2 cell lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected Pex3 in 10 µg of HepG2 cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
MABC550 04055977159271