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ST1716 Anti-IF Mouse mAb (1B3)

Anti-IF Mouse mAb (1B3) MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Anti-Complement Factor I

ST1716
  
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Overview

Replacement Information

Key Spec Table

Host
M
Description
Overview

This product has been discontinued.





Recognizes the IF protein.
Catalogue NumberST1716
Brand Family Calbiochem®
SynonymsAnti-Complement Factor I
Application Data
Detection of human IF by immunoblotting. Sample: Partial recombinant protein. Primary antibody: Anti-IF Mouse mAb (1B3) (Cat. No. ST1716) (1-5 µg/ml). Detection: chemiluminescence.
References
Product Information
Formliquid
FormulationIn PBS, pH 7.2.
PreservativeNone
Applications
Key Applications Enzyme-Linked Immunosorbent Assay
Immunoblotting (Western Blotting)
Application NotesELISA (see comments)
Immunoblotting (1-5 µg/ml)
Application CommentsFor ELISA, this antibody can be used as the capture antibody; recommended concentration is 10 ng/ml, 1 µg/well, 100 µl total volume. Variables associated with assay conditions will dictate the proper working dilution.
Biological Information
ImmunogenA recombinant polypeptide corresponding to amino acids of 19-119 human IF, expressed as a GST fusion protein
Clone1B3
HostMouse
IsotypeIgG2b
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Blue Ice Only
Toxicity Regulatory Review
Storage -20°C
Avoid freeze/thaw Avoid freeze/thaw
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
ST1716 0

Documentation

Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision10-November-2010 RFH
SynonymsAnti-Complement Factor I
ApplicationELISA (see comments)
Immunoblotting (1-5 µg/ml)
Application Data
Detection of human IF by immunoblotting. Sample: Partial recombinant protein. Primary antibody: Anti-IF Mouse mAb (1B3) (Cat. No. ST1716) (1-5 µg/ml). Detection: chemiluminescence.
DescriptionPurified mouse monclonal antibody. Recognizes the IF protein.
BackgroundThis gene encodes a serine proteinase that is essential for regulating the complement cascade. The encoded preproprotein is cleaved to produce both heavy and light chains, which are linked by disulfide bonds to form a heterodimeric glycoprotein. This heterodimer can cleave and inactivate the complement components C4b and C3b, and it prevents the assembly of the C3 and C5 convertase enzymes. Defects in this gene cause complement factor I deficiency, an autosomal recessive disease associated with a susceptibility to pyogenic infections. Mutations in this gene have been associated with a predisposition to atypical hemolytic uraemic syndrome, a disease characterized by acute renal failure, microangiopathic hemolytic anemia and thrombocytopenia. Primary glomerulonephritis with immmune deposits is another condition associated with mutation of this gene.
HostMouse
ImmunogenA recombinant polypeptide corresponding to amino acids of 19-119 human IF, expressed as a GST fusion protein
Clone1B3
IsotypeIgG2b
Specieshuman
Formliquid
FormulationIn PBS, pH 7.2.
PreservativeNone
CommentsFor ELISA, this antibody can be used as the capture antibody; recommended concentration is 10 ng/ml, 1 µg/well, 100 µl total volume. Variables associated with assay conditions will dictate the proper working dilution.
Storage Avoid freeze/thaw
-20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
Toxicity Regulatory Review