Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

ABT274 Anti-Decorin Antibody

Anti-Decorin Antibody is an antibody against Decorin for use in Immunohistochemistry, Western Blotting.

Anti-Decorin Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Cell Structure Research Sub-Category: Adhesion (CAMs) Gene Symbol: Dcn UniProt Number: P28654
ABT274
200 µL  
Purchase on Sigma-Aldrich

Special Offers

Overview

Replacement Information

Special Offers

100% Performance Guaranteed

Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
MIHC, WBRbSerumPolyclonal Antibody
Description
Catalogue NumberABT274
DescriptionAnti-Decorin Antibody
Alternate Names
  • Decorin
  • Bone proteoglycan II
  • PG-S2
  • PG40
Background InformationDecorin (UniProt P28654; also known as Bone proteoglycan II, PG40, PG-S2) is encoded by the Dcn (also known as DC, DSPG2, mDcn, PGII, SLRR1B) gene (Entrez Gene ID 13179) in murine. Decorin is a pericellular matrix proteoglycan structurally related to two other small proteoglycans, biglycan and fibromodulin. Decorin and biglycan are thought to be the result of a gene duplication. Decorin contains one attached glycosaminoglycan chain, while biglycan contains two chains. Decorin modulates collagen fibril formation as well as the bioactivity of various members of the transforming growth factor-beta (TGFbeta) superfamily. Decorin is initially translated as a preproprotein with an N-terminal signal peptide (aa1-16) and propeptide (aa17-30) sequence. Sequential removal of the signal peptide and the propeptide sequence produces pro- and mature decorin, respectively. (PMID 20026052).
References
Product Information
FormatSerum
PresentationRabbit polyclonal antibody serum with 0.05% sodium azide.
Quality LevelMQ300
Applications
ApplicationAnti-Decorin Antibody is an antibody against Decorin for use in Immunohistochemistry, Western Blotting.
Key Applications
  • Immunohistochemistry
  • Western Blotting
Application NotesWestern Blotting Analysis: A 1:1,000 dilution from a representative lot detected Decorin in mouse knee joint extract.
Biological Information
ImmunogenCSA-conjugated linear peptide corresponding to the mature chain of mouse Decorin.
ConcentrationPlease refer to lot specific datasheet.
HostRabbit
SpecificityReacts with decorin preproprotein, pro-decorin, as well as the mature decorin. This polyclonal antiserum is also known by LF-114.
Species Reactivity
  • Mouse
Species Reactivity NoteMouse. Predicted to react with Rat based on 100% sequence homology.
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • Dcn
Purification MethodUnpurified
UniProt Number
Molecular Weight39.7 kDa calculated
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Immunohistochemistry in mouse skin tissue.

Immunohistochemistry Analysis: A 1:500 dilution of this antibody detected Decorin in mouse skin tissue.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Packaging Information
Material Size200 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
ABT274 04055977169232