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ABC343 Anti-Caspase-10 Antibody

Detect Caspase 10 using this rabbit polyclonal antibody, Anti-Caspase-10 Antibody validated for use in western blotting.

Anti-Caspase-10 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Apoptosis & Cancer Research Sub-Category: Apoptosis - Additional Gene Symbol: CASP10 UniProt Number: Q92851
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ABC343
100 µg  
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Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWBRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABC343
DescriptionAnti-Caspase-10 Antibody
Alternate Names
  • Casp-10
  • Caspase-10
Background InformationCaspase-10 is a member of the peptidase C14A family and is involved in the activation cascade of caspases responsible for apoptosis execution. Caspase-10 has two death effector domains (DEDs) that bind to the DED in the adapter molecule FADD and recruits both TNFR1 and CD95 to form complexes with these receptors. Caspase-10 is expressed in many tissues and cell lines with the lowest expression found in brain, kidney, prostate, testis, and colon. Mutations in Caspase-10 have been associated with autoimmune lymphoproliferative syndrome type 2A and gastric cancer.
References
Product Information
FormatAffinity Purified
Control
  • HeLa, Jurkat, A431, and K562 whole cell lysates
PresentationPurified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
Quality LevelMQ100
Applications
ApplicationDetect Caspase 10 using this rabbit polyclonal antibody, Anti-Caspase-10 Antibody validated for use in western blotting.
Key Applications
  • Western Blotting
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to the C-terminus of human Caspase-10.
EpitopeC-terminus
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
SpecificityThis antibody recognizes the C-terminus of Caspase-10.
Species Reactivity
  • Human
Antibody TypePolyclonal Antibody
Gene Symbol
  • CASP10
Purification MethodAntigen Affinity Purified
UniProt Number
Molecular Weight~59 kDa observed. Uniprot describes 6 isoforms ranging from ~31 kDa to ~59 kDa. Uncharacterized bands may appear in some lysates.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in HeLa, Jurkat, A431, and K562 whole cell lysates.

Western Blotting Analysis: 1 µg/mL of this antibody detected Caspase-10 in 15 µg of HeLa, Jurkat, A431, and K562 whole cell lysates.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
ABC343 04053252862731