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MABS419 Anti-BMPR-1A, clone 4B7B2 Antibody

This Anti-BMPR-1A, clone 4B7B2 Antibody is validated for use in western blotting, IHC, flow cytometry & ELISA for the detection of BMPR-1A.

Anti-BMPR-1A, clone 4B7B2 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Signaling Research Sub-Category: Developmental Signaling Gene Symbol: BMPR1A, ACVRLK3, ALK3 UniProt Number: P36894
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MABS419
100 µL  
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Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, MWB, IHC, FC, ELISAMAscitesMonoclonal Antibody
Description
Catalogue NumberMABS419
DescriptionAnti-BMPR-1A, clone 4B7B2 Antibody
Alternate Names
  • Bone morphogenetic protein receptor type-1A
  • BMP type-1A receptor
  • BMPR-1A
Background InformationBMPR-1A (bone morphogenic protein receptor type 1A) signaling is known to be important for inner root sheath differentiation, hair follicle cycling and tooth development. Mutations in BMPR-1A are a common cause of juvenile polyposis syndrome (JPS). BMPR-1A is expressed in a high quantity during the formation of the primary and secondary palate and the loss of BMPR-1A could be a cause for the cleft palate birth defect.
References
Product Information
FormatAscites
PresentationMouse monoclonal IgG1 ascitic fluid containing up to 0.1% sodium azide.
Quality LevelMQ100
Applications
ApplicationThis Anti-BMPR-1A, clone 4B7B2 Antibody is validated for use in western blotting, IHC, flow cytometry & ELISA for the detection of BMPR-1A.
Key Applications
  • Western Blotting
  • Immunohistochemistry
  • Flow Cytometry
  • ELISA
Application NotesImmunohistochemistry Analysis: A 1:200-1,000 dilution from a representative lot detected BMPR-1A in colon cancer and kidney tissues.

Flow Cytometry Analysis: A 1;200-400 dilution from a representative lot detected BMPR-1A in HeLa cells.

ELISA: A representative lot detected control Antigen (100 ng) and Antigen (10 ng, 50 ng, 100 ng) in ELISA (Direct).
Biological Information
ImmunogenPurified recombinant fragment of human BMPR1A expressed in E. Coli
Clone4B7B2
HostMouse
IsotypeIgG1
Species Reactivity
  • Human
  • Mouse
Antibody TypeMonoclonal Antibody
Gene Symbol
  • BMPR1A
  • ACVRLK3
  • ALK3
Purification MethodUnpurified
UniProt Number
Molecular Weight~65 kDa observed. Uncharacterized bands may be observed in some lysate(s).
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in PC-3, K562 and mouse liver lysates.

Western Blotting Analysis: A 1:500-2,000 dilution of this antibody detected BMPR-1A in PC-3, K562 and mouse liver lysates.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
MABS419 04053252957826

Documentation

Anti-BMPR-1A, clone 4B7B2 Antibody SDS

Title

Safety Data Sheet (SDS) 

Anti-BMPR-1A, clone 4B7B2 Antibody Certificates of Analysis

TitleLot Number
Anti-BMPR-1A, clone 4B7B2 - QVP1312059 QVP1312059
Anti-BMPR-1A, clone 4B7B2 - VP1912271 VP1912271
Anti-BMPR-1A, clone 4B7B2 - VP2401022 VP2401022
Anti-BMPR-1A, clone 4B7B2 -VP1410295 VP1410295
Anti-BMPR-1A, clone 4B7B2 -VP1508203 VP1508203
Anti-BMPR-1A, clone 4B7B2 -VP1601281 VP1601281
Anti-BMPR-1A, clone 4B7B2 -VP1601281A VP1601281A
Anti-BMPR-1A, clone 4B7B2 -VP1603027 VP1603027
Anti-BMPR-1A, clone 4B7B2 -VP1608180 VP1608180
Anti-BMPR-1A, clone 4B7B2 Monoclonal Antibody VP1703251