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AP1138 Anti-ARSA Mouse pAb

Anti-ARSA, mouse polyclonal, recognizes the ~55 kDa ARSA protein in human lymph node tissue. It is validated for Western blotting and paraffin sections.

Anti-ARSA Mouse pAb MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
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AP1138
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Overview

Replacement Information

Key Spec Table

Species ReactivityHostAntibody Type
HMPolyclonal Antibody

Products

Catalogue NumberPackaging Qty/Pack
AP1138-50UG 50 μg
Description
OverviewRecognizes the ~55 kDa ARSA protein in human lymph node tissue.
Catalogue NumberAP1138
Brand Family Calbiochem®
Application Data
Detection of human ARSA by immunoblotting. Sample: Whole cell lysate from 293T cells transfected with human ARSA (lane 1) non-transfected 293T cells (lane 2). Primary antibody: Anti-ARSA Mouse pAb (Cat. No. AP1138) (1-5 µg/ml). Detection: chemiluminescence.

Detection of human ARSA by staining paraffin sections. Sample: Formalin/PFA-fixed, paraffin-embedded human lymph node tissue. Primary antibody: Anti-ARSA Mouse pAb (Cat. No. AP1138) (3 µg/ml). Detection: colrimetric (DAB).
References
Product Information
FormLiquid
FormulationIn PBS, pH 7.2.
Positive controlHuman lymph node tissue
PreservativeNone
Quality LevelMQ100
Applications
Key Applications Immunoblotting (Western Blotting)
Paraffin Sections
Application NotesImmunoblotting (1-5 µg/ml)
Paraffin Sections (3 µg/ml)
Application CommentsVariables associated with assay conditions will dictate the proper working dilution.
Biological Information
ImmunogenFull length human ARSA (aa 1-507)
ImmunogenHuman
HostMouse
IsotypeIgG
Species Reactivity
  • Human
Antibody TypePolyclonal Antibody
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Blue Ice Only
Toxicity Regulatory Review
Storage -20°C
Avoid freeze/thaw Avoid freeze/thaw
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
AP1138-50UG 04055977227833

Documentation

Anti-ARSA Mouse pAb SDS

Title

Safety Data Sheet (SDS) 

Anti-ARSA Mouse pAb Certificates of Analysis

TitleLot Number
AP1138
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision20-October-2010 JLN
ApplicationImmunoblotting (1-5 µg/ml)
Paraffin Sections (3 µg/ml)
Application Data
Detection of human ARSA by immunoblotting. Sample: Whole cell lysate from 293T cells transfected with human ARSA (lane 1) non-transfected 293T cells (lane 2). Primary antibody: Anti-ARSA Mouse pAb (Cat. No. AP1138) (1-5 µg/ml). Detection: chemiluminescence.

Detection of human ARSA by staining paraffin sections. Sample: Formalin/PFA-fixed, paraffin-embedded human lymph node tissue. Primary antibody: Anti-ARSA Mouse pAb (Cat. No. AP1138) (3 µg/ml). Detection: colrimetric (DAB).
DescriptionPurified mouse polyclonal antibody. Recognizes the ~55 kDa ARSA protein.
BackgroundARSA hydrolyzes cerebroside sulfate. Defects in ARSA are known to cause metachromatic leukodystrophy (MLD). MLD is a disease due to a lysosomal storage defect. It is characterized by intralysosomal storage of cerebroside-3-sulfate in neural and non-neural tissues, with a diffuse loss of myelin in the central nervous system. Progressive demyelination causes a variety of neurological symptoms, including gait disturbances, ataxias, optical atrophy, dementia, seizures, and spastic tetraparesis. Three forms of the disease can be distinguished according to the age at onset: late-infantile, juvenile and adult.
HostMouse
Immunogen speciesHuman
ImmunogenFull length human ARSA (aa 1-507)
IsotypeIgG
Specieshuman
Positive controlHuman lymph node tissue
FormLiquid
FormulationIn PBS, pH 7.2.
PreservativeNone
CommentsVariables associated with assay conditions will dictate the proper working dilution.
Storage Avoid freeze/thaw
-20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
Toxicity Regulatory Review