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GF300 Activin A Protein, Human Recombinant Animal Free

Activins, members of the TGF-beta superfamily, are disulfide-linked dimeric proteins purified from gonadal fluids as proteins that stimulated pituitary follicle stimulating hormone (FSH) release.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
UniProt Number: P08476
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GF300
10 µg  
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Overview

Key Spec Table

SourcePurity
E. coli Product is endotoxin free (< 0.1ng/μg of protein (<1EU/μg) and greater than 97% pure by SDS-PAGE gel and HPLC analyses
Description
Catalogue NumberGF300
Trade Name
  • Chemicon
DescriptionActivin A Protein, Human Recombinant Animal Free
Alternate Names
  • Inhibin
  • Activin-A
  • Erythroid differentiation protein
Background InformationActivins, members of the TGF-beta superfamily, are disulfide-linked dimeric proteins originally purified from gonadal fluids as proteins that stimulated pituitary follicle stimulating hormone (FSH) release. Activin proteins have a wide range of biological activities, including mesoderm induction, neural cell differentiation, bone remodeling, hematopoiesis and roles in reproductive physiology. The biological activities of Activin A can be neutralized by inhibins and by the diffusible TGF-β antagonist, follistatin. Recombinant human Activin A is a 26.0 kDa disulfide-linked homodimer of two βA chains, each containing 116 amino acid residues.
Product Information
Formulation
PresentationProduct is filtered through a 0.2 micron filter before lyophilization.
Quality LevelMQ100
Applications
ApplicationActivins, members of the TGF-beta superfamily, are disulfide-linked dimeric proteins purified from gonadal fluids as proteins that stimulated pituitary follicle stimulating hormone (FSH) release.
Biological Information
PurityProduct is endotoxin free (< 0.1ng/μg of protein (<1EU/μg) and greater than 97% pure by SDS-PAGE gel and HPLC analyses
SourceE. coli
Cross ReactivityChicken, Dog, Frog, Mouse, Human and Mouse
UniProt Number
Product Usage Statements
Quality AssuranceBioactivity assay: determined by its ability to inhibit the proliferation of mouse MPC-11 cells. The expected ED50 is ≤ 2.0 ng/ml, corresponding to a specific activity of ≥ 5 x 105 units/mg.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStore at -20°C for up to 6 months from date of receipt.
Packaging Information
Material Size10 µg
Global Trade Item Number
Catalogue Number GTIN
GF300 04053252691416