Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

178221 α₂-Antiplasmin, Human Plasma - Calbiochem

A 452-amino acid glycoprotein present in plasma at about 70 µg/ml.

α₂-Antiplasmin, Human Plasma - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: α₂-Protease Inhibitor, Primary Plasmin Inhibitor

Primary Target: Plasminogen activator-induced lysis of fibrin clots
View Products on Sigmaaldrich.com
178221
Purchase on Sigma-Aldrich

Overview

Replacement Information

Products

Catalogue NumberPackaging Qty/Pack
178221-100UG Plastic ampoule 100 μg
Description
OverviewA 452-amino acid glycoprotein present in plasma at about 70 µg/ml. Efficiently inhibits the plasminogen activator-induced lysis of fibrin clots. Forms a covalent complex with plasmin and inactivates it.
Catalogue Number178221
Brand Family Calbiochem®
Synonymsα₂-Protease Inhibitor, Primary Plasmin Inhibitor
References
ReferencesSchaefer, B.M., et al. 1996. Arch. Dermatol. Res. 288, 122.
Aoki, N., et al. 1980. Blood 55, 483.
Saito, H., et al. 1974. Circ. Res. 34, 641.
Product Information
Unit of DefinitionOne Inhibitory Unit (I.U.) is defined as the amount of enzyme that will inhibit 1 unit plasmin activity using tosyl-Gly-Pro-Lys-<i>p</i>NA as substrate at 25°C, pH 7.8
ATP CompetitiveN
FormSolid
FormulationLyophilized from 200 mM NaCl, 20 mM Bis-Tris, pH 6.4.
ReversibleN
Quality LevelMQ100
Applications
Biological Information
Primary TargetPlasminogen activator-induced lysis of fibrin clots
Purity≥95% by SDS-PAGE
SourcePrepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Specific Activity≥5 I.U./mg protein
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
178221-100UG 04055977223101

Documentation

α₂-Antiplasmin, Human Plasma - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

α₂-Antiplasmin, Human Plasma - Calbiochem Certificates of Analysis

TitleLot Number
178221

References

Reference overview
Schaefer, B.M., et al. 1996. Arch. Dermatol. Res. 288, 122.
Aoki, N., et al. 1980. Blood 55, 483.
Saito, H., et al. 1974. Circ. Res. 34, 641.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision02-May-2008 JSW
Synonymsα₂-Protease Inhibitor, Primary Plasmin Inhibitor
DescriptionA 452-amino acid glycoprotein present in plasma at about 70 µg/ml. Efficiently inhibits the plasminogen-activator-induced lysis of fibrin clots. Forms a covalent complex with plasmin and inactivates it.
FormSolid
FormulationLyophilized from 200 mM NaCl, 20 mM Bis-Tris, pH 6.4.
SourcePrepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Purity≥95% by SDS-PAGE
Specific activity≥5 I.U./mg protein
Unit definitionOne Inhibitory Unit (I.U.) is defined as the amount of enzyme that will inhibit 1 unit plasmin activity using tosyl-Gly-Pro-Lys-pNA as substrate at 25°C, pH 7.8
SolubilityH₂O. Please refer to the vial label for the lot-specific reconstitution volume.
Storage -20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Toxicity Standard Handling
ReferencesSchaefer, B.M., et al. 1996. Arch. Dermatol. Res. 288, 122.
Aoki, N., et al. 1980. Blood 55, 483.
Saito, H., et al. 1974. Circ. Res. 34, 641.