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260575 1-Deoxymannojirimycin, Hydrochloride - CAS 84444-90-6 - Calbiochem

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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
84444-90-6C₆H₁₃NO₄·HCl
Description
OverviewA specific α-mannosidase I inhibitor that blocks conversion of high mannose to complex oligosaccharides.
Catalogue Number260575
Brand Family Calbiochem®
SynonymsDMJ, 1,5-Dideoxy-1,5-imino-D-mannitol, HCl
References
ReferencesSuzuki, S.S., and Piette, L.H. 1993. J. Cell. Biochem. 51, 181.
Fuhrmann, U., et al. 1984. Nature 307, 755.
Product Information
CAS number84444-90-6
ATP CompetitiveN
FormWhite crystalline solid
Hill FormulaC₆H₁₃NO₄·HCl
Chemical formulaC₆H₁₃NO₄·HCl
Hygroscopic Hygroscopic
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary Targetα-mannosidase-I
Purity≥98% by TLC
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
R PhraseR: 20/21/22

Harmful by inhalation, in contact with skin and if swallowed.
S PhraseS: 36

Wear suitable protective clothing.
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Harmful
Storage -20°C
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) for long term storage or refrigerate (4°C) for short term storage. Stock solutions are stable for up to 1 month at 4°C or for up to 6 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
260575 0

Documentation

1-Deoxymannojirimycin, Hydrochloride - CAS 84444-90-6 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

1-Deoxymannojirimycin, Hydrochloride - CAS 84444-90-6 - Calbiochem Certificates of Analysis

TitleLot Number
260575

References

Reference overview
Suzuki, S.S., and Piette, L.H. 1993. J. Cell. Biochem. 51, 181.
Fuhrmann, U., et al. 1984. Nature 307, 755.

Citations

Title
  • William D. Hanley, et al. (2005) CD44 on LS174T Colon Carcinoma Cells Possesses E-Selectin Ligand Activity. Cancer Research 65, 5812-5817.
  • Jenny J.L. Ho, et al. (2003) N-glycosylation is required for the surface localization of MUC17 mucin. 23, 585-592.
  • Data Sheet

    Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

    Revision28-April-2008 JSW
    SynonymsDMJ, 1,5-Dideoxy-1,5-imino-D-mannitol, HCl
    DescriptionSpecial α-mannosidase I inhibitor that blocks conversion of high mannose to complex oligosaccharides.
    FormWhite crystalline solid
    Intert gas (Yes/No) Packaged under inert gas
    CAS number84444-90-6
    Chemical formulaC₆H₁₃NO₄·HCl
    Structure formulaStructure formula
    Purity≥98% by TLC
    SolubilityEthanol (1 mg/ml) or H₂O (1 mg/ml)
    Storage -20°C
    Hygroscopic
    Do Not Freeze Ok to freeze
    Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) for long term storage or refrigerate (4°C) for short term storage. Stock solutions are stable for up to 1 month at 4°C or for up to 6 months at -20°C.
    Toxicity Harmful
    ReferencesSuzuki, S.S., and Piette, L.H. 1993. J. Cell. Biochem. 51, 181.
    Fuhrmann, U., et al. 1984. Nature 307, 755.
    Citation
  • William D. Hanley, et al. (2005) CD44 on LS174T Colon Carcinoma Cells Possesses E-Selectin Ligand Activity. Cancer Research 65, 5812-5817.
  • Jenny J.L. Ho, et al. (2003) N-glycosylation is required for the surface localization of MUC17 mucin. 23, 585-592.