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14-938M TLK1, active

TLK1, active MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
14-938M
250 µg  Also available in 10μg size as catalog # 14-938 and in bulk as catalog # 14-938-K.
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      Overview

      Replacement Information
      Description
      Catalogue Number14-938M
      Trade Name
      • Upstate
      DescriptionTLK1, active
      OverviewThis protein is a serine/threonine kinase that may be involved in the regulation of chromatin assembly. The protein is only active when it is phosphorylated, and this phosphorylation is cell cycle-dependent, with the maximal activity of this protein coming during S phase. The catalytic activity of this protein is diminished by DNA damage and by blockage of DNA replication. Three transcript variants encoding different isoforms have been found for this gene.
      References
      Product Information
      PresentationProtein in 50mM Tris/HCl pH7.5, 300mM NaCl, 0.1mM EGTA, 0.03% Brij-35, 270mM sucrose, 1mM benzamidine, 0.2mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution.
      Quality LevelMQ100
      Applications
      Key Applications
      • Kinase Assay
      Biological Information
      SourceN-terminal 6His-tagged, recombinant, human TLK1 full length, expressed by baculovirus in Sf21 insect cells.
      Specific ActivityFor Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
      Entrez Gene Number
      Gene Symbol
      • TLK1
      • PKU-Beta
      Purification MethodPurified using immobilized metal affinity chromatography.
      UniProt Number
      Molecular Weight91 kDa
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceRoutinely evaluated by phosphorylation of casein
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage Conditions6 months at -70°C
      Packaging Information
      Material Size250 µg
      Material PackageAlso available in 10μg size as catalog # 14-938 and in bulk as catalog # 14-938-K.
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      14-938M 04053252946264

      Related Products & Applications

      Alternative Packsize

      Catalogue Number Description  
      14-938 TLK1, active Show Pricing & Availability

      Product Families

      Kinase & Phosphatase Products

      Millipore offers a large portfolio of Kinases, Phophatases, Substrates, Inhibitors, Kits, reagents & tools for Signaling research. See below for a list of these products, in multiple pack sizes.
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      Categories

      Life Science Research > Proteins and Enzymes > Purified Kinases
      Life Science Research > Drug Discovery and Development > Kinase & Phosphatase Screening > Purified Kinases