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559290 S-100b Protein, Bovine Brain

S-100b Protein, Bovine Brain MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
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559290
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Overview

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559290-1MG
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      		 Plastic ampoule 1 mg
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      Description
      OverviewNative homodimeric S-100b isoform composed of ββ-subunits, purified from bovine brain. Elevated serum level of S-100b is used as a marker of stroke and cerebral edema.
      Catalogue Number559290
      Brand Family Calbiochem®
      References
      ReferencesMomotani, E., et al. 1993. J. Comp. Pathol. 108, 291.
      Baudier, J., et al. 1992. Proc. Natl. Acad. Sci. USA 89, 11627.
      Donato, R. 1991. Cell Calcium 12, 713.
      Isobe, T., et al. 1977. Biochim. Biophys. Acta 494, 222.
      Product Information
      FormLyophilized
      FormulationLyophilized from 50 mM Tris-HCl, pH 7.5, 50 mM NaCl, 100 µM DTT.
      Quality LevelMQ100
      Applications
      Biological Information
      Purity≥95% by SDS-PAGE
      Physicochemical Information
      ContaminantsS100 α-chain: ≤10% by Western Blot
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      559290-1MG 04055977192384

      Documentation

      S-100b Protein, Bovine Brain SDS

      Title

      Safety Data Sheet (SDS) 

      S-100b Protein, Bovine Brain Certificates of Analysis

      TitleLot Number
      559290

      References

      Reference overview
      Momotani, E., et al. 1993. J. Comp. Pathol. 108, 291.
      Baudier, J., et al. 1992. Proc. Natl. Acad. Sci. USA 89, 11627.
      Donato, R. 1991. Cell Calcium 12, 713.
      Isobe, T., et al. 1977. Biochim. Biophys. Acta 494, 222.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision27-January-2014 JSW
      DescriptionThe homodimeric S-100 isoform composed of ββ-subunits, purified from bovine brain. The S-100 proteins are acidic Ca2+ binding proteins found predominately in glial cells. Evidence indicates that upon binding to Ca2+, S-100 proteins expose a hydrophobic domain to the solvent in a manner similar to calmodulin. Within the cell, S-100 proteins have been reported to regulate adenylate cyclase, aldolase activities, ATPase, microtubules, and protein phosphorylation. Under nonreducing conditions both the dimeric and monomeric forms may be visible.

      Note: This product is not to be used for animal treatment, in vivo research or in any other contact procedure with livestock.
      FormLyophilized
      FormulationLyophilized from 50 mM Tris-HCl, pH 7.5, 50 mM NaCl, 100 µM DTT.
      Purity≥95% by SDS-PAGE
      ContaminantsS100 α-chain: ≤10% by Western Blot
      Solubility50 mM Tris buffer, pH 8.0 (5 mg/ml)
      Storage -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Toxicity Standard Handling
      ReferencesMomotani, E., et al. 1993. J. Comp. Pathol. 108, 291.
      Baudier, J., et al. 1992. Proc. Natl. Acad. Sci. USA 89, 11627.
      Donato, R. 1991. Cell Calcium 12, 713.
      Isobe, T., et al. 1977. Biochim. Biophys. Acta 494, 222.