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480066 Necrostatin-1, Inactive Control - CAS 64419-92-7 - Calbiochem

Necrostatin-1, Inactive Control, CAS 64419-92-7, is a cell-permeable N-demethylated thiohydantoin analog of Nec-1 (Cat. No. 480065) without anti-necroptotic properties.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 5-(Indol-3-ylmethyl)-2-thiohydantoin, Nec-1i

Primary Target: Inactive control for Nec-1 (Cat. No. 480065)
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480066
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
64419-92-7C₁₂H₁₁N₃OS

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      Description
      OverviewA cell-permeable N-demethylated thiohydantoin analog of Nec-1 (Cat. No. 480065) that is devoid of anti-necroptotic properties and serves as a suitable inactive control.

      Note: This inactive inhibitor of necrosis should not be used in high concentration.
      Catalogue Number480066
      Brand Family Calbiochem®
      Synonyms5-(Indol-3-ylmethyl)-2-thiohydantoin, Nec-1i
      References
      ReferencesTakahashi et al. 2012. Cell Death and Disease 3, e437.
      Degterev, A., et al. 2005. Nat. Chem. Biol. 1, 112.
      Product Information
      CAS number64419-92-7
      ATP CompetitiveN
      FormLight yellow crystalline solid
      Hill FormulaC₁₂H₁₁N₃OS
      Chemical formulaC₁₂H₁₁N₃OS
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      ApplicationNecrostatin-1, Inactive Control, CAS 64419-92-7, is a cell-permeable N-demethylated thiohydantoin analog of Nec-1 (Cat. No. 480065) without anti-necroptotic properties.
      Biological Information
      Primary TargetInactive control for Nec-1 (Cat. No. 480065)
      Purity≥95% by HPLC
      Physicochemical Information
      Cell permeableY
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      480066-5MG 04055977201888

      Documentation

      Necrostatin-1, Inactive Control - CAS 64419-92-7 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      Necrostatin-1, Inactive Control - CAS 64419-92-7 - Calbiochem Certificates of Analysis

      TitleLot Number
      480066

      References

      Reference overview
      Takahashi et al. 2012. Cell Death and Disease 3, e437.
      Degterev, A., et al. 2005. Nat. Chem. Biol. 1, 112.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision14-January-2015 JSW
      Synonyms5-(Indol-3-ylmethyl)-2-thiohydantoin, Nec-1i
      DescriptionA cell-permeable N-demethylated thiohydantoin analog of Nec-1 (Cat. No. 480065) that is devoid of anti-necroptotic properties and serves as a suitable inactive control.

      Note: This inactive inhibitor of necrosis should not be used in high concentration.
      FormLight yellow crystalline solid
      Intert gas (Yes/No) Packaged under inert gas
      CAS number64419-92-7
      Chemical formulaC₁₂H₁₁N₃OS
      Structure formulaStructure formula
      Purity≥95% by HPLC
      SolubilityDMSO (10 mg/ml) or Methanol (5 mg/ml)
      Storage Protect from light
      +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesTakahashi et al. 2012. Cell Death and Disease 3, e437.
      Degterev, A., et al. 2005. Nat. Chem. Biol. 1, 112.