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475870 MnTBAP - Calbiochem

MnTBAP, CAS 55266-18-7, is a cell-permeable superoxide dismutase (SOD) mimetic and peroxynitrite scavenger.

MnTBAP - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Mn(III)tetrakis(4-benzoic acid)porphyrin Chloride

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475870
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Overview

Key Spec Table

CAS #Empirical Formula
55266-18-7C₄₈H₂₈ClMnN₄O₈

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475870-25MG
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      Description
      OverviewCell-permeable superoxide dismutase (SOD) mimetic and peroxynitrite scavenger. Protects endothelial cells in a dose-dependent manner (EC50 ~40 µM) against paraquat (2 mM). Inhibits the oxidation of Dihydrorhodamine 123 (Cat. No. 309825) by peroxynitrite, but does not scavenge nitric oxide (NO).
      Catalogue Number475870
      Brand Family Calbiochem®
      SynonymsMn(III)tetrakis(4-benzoic acid)porphyrin Chloride
      References
      ReferencesAladag, M. A., et al. 2003. Acta Neurochir. 145, 673.
      Szabo, C., et al. 1996. FEBS Lett. 381, 82.
      Day, B.J., et al. 1995. J. Pharmacol. Exp. Ther. 275, 1227.
      Faulkner, K.M., et al. 1994. J. Biol. Chem. 269, 23471.
      Product Information
      CAS number55266-18-7
      ATP CompetitiveN
      FormBrown solid
      Hill FormulaC₄₈H₂₈ClMnN₄O₈
      Chemical formulaC₄₈H₂₈ClMnN₄O₈
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      ApplicationMnTBAP, CAS 55266-18-7, is a cell-permeable superoxide dismutase (SOD) mimetic and peroxynitrite scavenger.
      Biological Information
      Primary TargetSuperoxide dismutase (SOD) mimetic
      Primary Target IC<sub>50</sub>EC50 ~40 µM in protecting endothelial cells against paraquat (2 mM)
      Purity≥95% by TLC
      Physicochemical Information
      Cell permeableY
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Protect from Moisture Protect from moisture
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Global Trade Item Number
      Catalogue Number GTIN
      475870-25MG 07790788050467