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324740 Elastase Substrate V, Fluorogenic - CAS 72252-90-5 - Calbiochem

Elastase Substrate V, Fluorogenic, CAS 72252-90-5, is a sensitive fluorogenic substrate for the quantitative determination of human leukocyte and porcine pancreatic elastase (Km = 140 µM).

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: MeOSuc-AAPV-AMC

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324740
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324740-25MG
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      		 Plastic ampoule 25 mg
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      Description
      OverviewSensitive fluorogenic substrate for the quantitative determination of human leukocyte and porcine pancreatic elastase (Km = 140 µM; kcat/Km = 120,000 M-1 s-1). Not hydrolysed by cathepsin G.
      Catalogue Number324740
      Brand Family Calbiochem®
      SynonymsMeOSuc-AAPV-AMC
      References
      ReferencesBarrett, A.J. 1981. Methods Enzymol. 80, 581.
      Castillo, M.J., et al. 1979. Anal. Biochem. 99, 53.
      Nakajima, K., et al. 1979. J. Biol. Chem. 254, 4027.
      Product Information
      CAS number72252-90-5
      ATP CompetitiveN
      FormWhite to off-white lyophilized solid or powder
      Hill FormulaC₃₁H₄₁N₅O₉
      Chemical formulaC₃₁H₄₁N₅O₉
      ReversibleN
      Quality LevelMQ200
      Applications
      Biological Information
      Primary TargetSensitive fluorogenic substrate for the quantitative determination of human leukocyte and porcine pancreatic elastase
      Primary Target IC<sub>50</sub>Km = 140 µM; kcat/Km = 120,000 M⁻¹ s⁻¹as substrates for human leukocyte and porcine pancreatic elastase
      Purity≥95% by HPLC or TLC
      Physicochemical Information
      Cell permeableN
      Emission max.
      Excitation max.
      Peptide SequenceMeOSuc-Ala-Ala-Pro-Val-AMC
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Protect from Moisture Protect from moisture
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze at -20°C. Stock solutions are stable for up to 2 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      324740-25MG 04055977216042

      Documentation

      Elastase Substrate V, Fluorogenic - CAS 72252-90-5 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      Elastase Substrate V, Fluorogenic - CAS 72252-90-5 - Calbiochem Certificates of Analysis

      TitleLot Number
      324740

      References

      Reference overview
      Barrett, A.J. 1981. Methods Enzymol. 80, 581.
      Castillo, M.J., et al. 1979. Anal. Biochem. 99, 53.
      Nakajima, K., et al. 1979. J. Biol. Chem. 254, 4027.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision09-April-2018 JSW
      SynonymsMeOSuc-AAPV-AMC
      DescriptionSensitive fluorogenic substrate for the quantitative determination of human leukocyte (Km = 140 µM; Kcat/Km = 120,000 s-1 M-1) and porcine pancreatic elastase. Not hydrolyzed by cathepsin G. Excitation max.: ~380 nm; emission max.: ~460 nm.
      FormWhite to off-white lyophilized solid or powder
      CAS number72252-90-5
      Chemical formulaC₃₁H₄₁N₅O₉
      Peptide SequenceMeOSuc-Ala-Ala-Pro-Val-AMC
      Purity≥95% by HPLC or TLC
      SolubilityDMSO (5 mg/ml), DMF (5 mg/ml), or Ethanol (1 mg/ml)
      Storage Protect from moisture
      Protect from light
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze at -20°C. Stock solutions are stable for up to 2 months at -20°C.
      Toxicity Standard Handling
      ReferencesBarrett, A.J. 1981. Methods Enzymol. 80, 581.
      Castillo, M.J., et al. 1979. Anal. Biochem. 99, 53.
      Nakajima, K., et al. 1979. J. Biol. Chem. 254, 4027.