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05-829X-555 Anti-α-Tubulin Antibody, Alexa Fluor® 555 conjugate

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05-829X-555
100 µg  
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      Overview

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      Av, B, Gp, H, M, Po, RIFMAlexaFluor®555Monoclonal Antibody
      Description
      Catalogue Number05-829X-555
      Brand Family Chemicon®
      Trade Name
      • Upstate
      DescriptionAnti-α-Tubulin Antibody, Alexa Fluor® 555 conjugate
      Product Information
      FormatAlexaFluor®555
      PresentationProtein G purified immunoglobulin conjugated to Alexa Fluor® 555. Liquid in PBS containing 1% BSA, 0.05% Tween®-20 and 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-α-Tubulin Antibody, Alexa Fluor 555 conjugate detects level of α-Tubulin & has been published & validated for use in IF.
      Key Applications
      • Immunofluorescence
      Biological Information
      ImmunogenThe epitope recognized by this antibody has been mapped to amino acids 426-450 (AALEKDYEEVGVDSV-EGEGEEEGEE).
      CloneDM1A
      HostMouse
      SpecificityRecognizes α-Tubulin
      IsotypeIgG1
      Species Reactivity
      • Avian
      • Bovine
      • Guinea Pig
      • Human
      • Mouse
      • Pig
      • Rat
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryMicrotubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The genes encoding these microtubule constituents belong to the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. This gene encodes alpha tubulin and is highly similar to mouse and rat Tuba1 gene. Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells. This gene is one of three alpha-tubulin genes in a cluster on chromosome 12q.
      Gene Symbol
      • TUBA1A
      • hum-a-tub2
      • FLJ25113
      • B-ALPHA-1
      • TUBA3
      • hum-a-tub1
      Purification MethodProtein G Purified
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: Q71U36 # Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain.
      SIZE: 451 amino acids; 50136 Da
      SUBUNIT: Dimer of alpha and beta chains.
      PTM: Undergoes a tyrosination/detyrosination cycle, the cyclic removal and re-addition of a C-terminal tyrosine residue by the enzymes tubulin tyrosine carboxypeptidase (TTCP) and tubulin tyrosine ligase (TTL), respectively (By similarity).
      SIMILARITY: SwissProt: Q71U36 ## Belongs to the tubulin family.
      Molecular Weight50-60 kDa
      Product Usage Statements
      Quality AssuranceRoutinely evaluated by immunofluorescence
      Usage Statement
      • Alexa Fluor® is a registered trademark of Molecular Probes, Inc.
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain at 4°C for up to one year from date of receipt.
      Packaging Information
      Material Size100 µg
      Global Trade Item Number
      Catalogue Number GTIN
      05-829X-555 04053252334375