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ABS542 Anti-SSR1/TRAP alpha Antibody

ABS542
100 µL  
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      Overview

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, Ca, RWB, ICCRbSerumPolyclonal Antibody
      Description
      Catalogue NumberABS542
      DescriptionAnti-SSR1/TRAP alpha Antibody
      Alternate Names
      • Translocon-associated protein subunit alpha
      • TRAP-alpha
      • Signal sequence receptor subunit alpha
      • SSR-alpha
      • SSR1/TRAP alpha
      Background InformationTranslocon-associated protein subunit alpha (UniProt P43307), also known as SSR-alpha, TRAP-alpha, Signal sequence receptor subunit alpha, Translocon-associated protein alpha subunit) is encoded by the SSR1 gene in human. The translocation site (translocon), at which nascent polypeptides pass through the endoplasmic reticulum membrane, is formed by the association of the Sec61p complex, the TRAM protein, and the tetrameric "'translocon-associated protein" (TRAP) complex composed of four glycosylated transmembrane signal sequence receptor (SSR) proteins (SSR1/alpha, SSR2/beta, SSR3/gamma, SSR4/delta).
      Product Information
      FormatSerum
      PresentationRabbit polyclonal antibody serum with 0.05% sodium azide.
      Quality LevelMQ300
      Applications
      ApplicationAnti-SSR1/TRAP alpha Antibody is an antibody against SSR1/TRAP alpha for use in Western Blotting, Immunocytochemistry.
      Key Applications
      • Western Blotting
      • Immunocytochemistry
      Application NotesWestern Blotting Analysis: A representative lot detected SSR1/TRAP alpha in dog pancreatic stripped rough microsomes (SRM), reconstituted vesicles of SRM (Migliaccio, G., et al. (1992). J. Cell Biol. 117(1):15-25).
      Western Blotting Analysis: A representative lot detected SSR1/TRAP alpha in Jurkat and J558 cells (Lerner, R.S., et al. (2003). RNA. 9(9):1123-1137).
      Western Blotting Analysis: A representative lot detected SSR1/TRAP alpha in HeLa cells (Zhou, W., et al. (2011). J. Biol. Chem. 286(24):21687-21696).
      Immunocytochemistry Analysis: A representative lot detected SSR1/TRAP alpha in A549 cells treated with S470 vesicles (Bauman, S., et al. (2009). BMC Microbiol. 9:26).
      Immunocytochemistry Analysis: A representative lot detected SSR1/TRAP alpha in rat dorsal root ganglion (DRG) neurons (Merianda, T.T., et al. (2009). Mol. Cell. Neurosci. 40(2):128-142).
      Immunocytochemistry Analysis: A representative lot detected SSR1/TRAP alpha in COS7 and HeLa (Zhou, W., et al. (2011). J. Biol. Chem. 286(24):21687-21696).
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to the C-terminus of human SSR1/TRAP alpha.
      ConcentrationPlease refer to lot specific datasheet.
      HostRabbit
      Species Reactivity
      • Human
      • Canine
      • Rat
      Species Reactivity NoteHuman, Canine, and Rat. Predicted to react with Mouse, Bovine, Procine, Gorilla, Chimpanzee, Monkey, Horse, and Feline based on 100% sequence homology.
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • SSR1
      • TRAPA
      • PSEC0262
      Purification MethodUnpurified
      UniProt Number
      Molecular Weight~37/39 kDa observed. Expected to react with both isoforms. SSR1/TRAP often appears as a doublet, representing the target protein in different phosphorylation states.
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in HeLa and HepG2 cell lysate.

      Western Blotting Analysis: A 1:500 dilution of this antibody detected SSR1/TRAP alpha in of HeLa and HepG2 cell lysates.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at -20°C from date of receipt.
      Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
      Packaging Information
      Material Size100 µL
      Global Trade Item Number
      Catalogue Number GTIN
      ABS542 04055977167924