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ABF209 Anti-SLAMF2 (CD48 Antibody)

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ABF209
100 µg  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      RWBRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABF209
      DescriptionAnti-SLAMF2 (CD48 Antibody)
      Alternate Names
      • Signaling lymphocytic activation molecule family member 2
      • CD48
      • BCM
      • BLAST1
      • MEM-102
      • CD48 antigen
      • B-lymphocyte activation marker BLAST-1
      • BCM1 surface antigen
      • Leukocyte antigen MEM-102
      • SLAMF
      Background InformationThe signaling lymphocyte-activation molecule family member 2 (SLAMF2), also known as CD48, is a GPI-anchored protein that exists as both a soluble and membrane-associated form and is expressed in almost all leukocyte populations particularly in mitogen-stimulated human lymphocytes. SLAMF2 is a high-affinity ligand for SLAMF4, also known as 2B4, as well as a low-affinity ligand for CD2, and can thus can stimulate cells expressing these receptors. It has been shown to be an IL-3-induced activating receptor on eosinophils and is likely to be involved in promoting allergic inflammation. SLAMF2 is also thought to be involved in the IL-18/IL-18R signaling cascade in T and natural killer cells to produce interferon-gamma.
      References
      Product Information
      FormatAffinity Purified
      Control
      • Rat lung tissue lysate
      PresentationPurified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-SLAMF2 (CD48 Antibody) is a highly specific rabbit polyclonal antibody, that targets CD48 & has been tested in western blotting.
      Key Applications
      • Western Blotting
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to human SLAMF2.
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      Species Reactivity
      • Rat
      Species Reactivity NoteDemonstrated to react with Rat. Predicted to react with Human based on immunogen design.
      Antibody TypePolyclonal Antibody
      Gene Symbol
      • CD48
      • SLAMF2
      • BCM1
      Purification MethodAntigen Affinity Purified
      UniProt Number
      Molecular Weight~17 and ~28 kDa observed
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in rat lung tissue lysate.

      Western Blotting Analysis: 2 µg/mL of this antibody detected SLAMF2 in 15 µg of rat lung tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      ABF209 04053252906978