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MABN476 Anti-Paris/ZNF746 Antibody, clone N196/16

Anti-Paris/ZNF746 Antibody, clone N196/16 is a highly specific mouse monoclonal antibody & that targets Zinc Finger Protein & has been tested in western blotting.

Anti-Paris/ZNF746 Antibody, clone N196/16 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Neurodegenerative Diseases Gene Symbol: ZNF746, PARIS UniProt Number: Q6NUN9
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MABN476
100 µg  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, M, RWBMPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMABN476
      DescriptionAnti-Paris/ZNF746 Antibody, clone N196/16
      Alternate Names
      • Zinc finger protein 746
      • Parkin-interacting substrate
      • PARIS
      Background InformationZinc finger protein 746 (ZNF746) is also called Parkin-interacting substrate (PARIS). ZNF746 is a repressor of transcription that binds to promoters and represses the transcription of PGC-1-alpha (PPARGC1A), making it important to the regulation of neuron death. ZNF746 may also contribute to neurodegeneration in Parkinson disease.
      References
      Product Information
      FormatPurified
      Control
      • HEK293 cell lysate
      PresentationPurified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-Paris/ZNF746 Antibody, clone N196/16 is a highly specific mouse monoclonal antibody & that targets Zinc Finger Protein & has been tested in western blotting.
      Key Applications
      • Western Blotting
      Application NotesWestern Blotting Analysis: 1 µg/mL of this antibody detected Paris/ZNF746 in 10 µg of RAW264.7 cell lysate. Immunohistochemistry Analysis: A representative lot detected Paris/ZNF746 in rat brain tissue (Prof. J. Trimmer, University of California, Davis.).
      Biological Information
      ImmunogenRecombinant protein corresponding to the N-terminus of human Paris/ZNF746.
      EpitopeN-terminus
      CloneN196/16
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostMouse
      SpecificityThis antibody recognizes the N-terminus of ZNF746. This antibody does not cross react with ZNF783 or ZNF398 (Prof. J. Trimmer, University of California, Davis.).
      IsotypeIgG1κ
      Species Reactivity
      • Human
      • Mouse
      • Rat
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • ZNF746
      • PARIS
      Purification MethodProtein G Purified
      UniProt Number
      Molecular Weight~72 kDa observed. Uniprot describes 3 isoforms, two at 69 kDa and one at 49 kDa. This protein is ubiquitinated and has been observed at higher molecular weights (Shin, J. H., et al. (2011). Cell. 144(5):689-702.).
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in HEK293 cell lysate.

      Western Blotting Analysis: 1 µg/mL of this antibody detected Paris/ZNF746 in 10 µg of HEK293 cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      MABN476 04053252912443

      Documentation

      Anti-Paris/ZNF746 Antibody, clone N196/16 SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-Paris/ZNF746 Antibody, clone N196/16 Certificates of Analysis

      TitleLot Number
      Anti-Paris/ZNF746 clone N196/16 - 3251023 3251023
      Anti-Paris/ZNF746 clone N196/16 - 3462123 3462123
      Anti-Paris/ZNF746 clone N196/16 - 3521077 3521077
      Anti-Paris/ZNF746 clone N196/16 - 3698723 3698723
      Anti-Paris/ZNF746 clone N196/16 - 3831722 3831722
      Anti-Paris/ZNF746 clone N196/16 - 3988531 3988531
      Anti-Paris/ZNF746 clone N196/16 - 4138112 4138112
      Anti-Paris/ZNF746 clone N196/16 - 4158362 4158362
      Anti-Paris/ZNF746 clone N196/16 - Q2204790 Q2204790
      Anti-Paris/ZNF746 clone N196/16 -2809944 2809944
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