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MABT27 Anti-LIBS2 epitope (Integrin beta3 subunit) Antibody, clone ab62

Anti-LIBS2 epitope (Integrin beta3 subunit) Antibody, clone ab62 is an antibody against LIBS2 epitope (Integrin beta3 subunit) for use in WB, FC.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Cell Structure Research Sub-Category: Integrins Gene Symbol: LIBS2
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MABT27
100 µg  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWB, FCMPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMABT27
      DescriptionAnti-LIBS2 epitope (Integrin beta3 subunit) Antibody, clone ab62
      Alternate Names
      • LIBS2 domain, Integrin, Integrin alphaVbeta3, LIBS2 epitiope
      Background InformationThe integrin family of cell adhesion receptors consists of at least 16 membrane-associated heterodimers, composed of an alpha and beta subunit that associate in a non-covalent manner. The involvement of integrins in vascular proliferation, adhesion, and wound repair has been well documented. The adhesion receptor, integrin alphaVbeta3, appears to be selectively expressed on growing blood vessels and has been identified as a marker of angiogenic vascular tissue.
      Clone Ab62 is a monoclonal antibody that specifically recognizes the LIBS2 epitope in the C-terminal region of the extracellular domain of the beta3 subunit (Wiberzbicka-Patynowski, I., et al. (1999). JBC. 274(53):37809-37814).
      References
      Product Information
      FormatPurified
      Control
      • Human platelets cell lysate
      PresentationPurified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-LIBS2 epitope (Integrin beta3 subunit) Antibody, clone ab62 is an antibody against LIBS2 epitope (Integrin beta3 subunit) for use in WB, FC.
      Key Applications
      • Western Blotting
      • Flow Cytometry
      Application NotesFlow Cytometry Analysis: A previous lot was used by an independent laboratory in FC (Ginsberg, M., et al. (1990). Blood. 76:2017-2023.)
      Biological Information
      ImmunogenHuman GPIIa-IIIb purified from platelets
      EpitopeLIBS2 epitope in the C-terminal region of the extracellular domain of the beta3 subunit of integrins.
      Cloneab62
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostMouse
      SpecificityThis antibody recognizes the LIBS2 epitope in the C-terminal region of the extracellular domain of the beta3 subunit of integrins.
      IsotypeIgG2aκ
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Gene Symbol
      • LIBS2
      Purification MethodProtein G Purified
      Molecular Weight~110 kDa observed in human platelets.
      Other MW bands may vary or may be observed depending on lysate used and if the LIBS2 epitope is present in other proteins.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blot in human platelets cell lysate.

      Western Blot Analysis: 0.5 µg/mL of this antibody detected LIBS2 domain of integrin beta3 subunit in 10 µg of human platelets cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      MABT27 04053252554360

      Documentation

      Anti-LIBS2 epitope (Integrin beta3 subunit) Antibody, clone ab62 SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-LIBS2 epitope (Integrin beta3 subunit) Antibody, clone ab62 Certificates of Analysis

      TitleLot Number
      Anti-LIBS2 epitope (Integrin beta3 subunit), clone ab62 - 2389002 2389002
      Anti-LIBS2 epitope (Integrin beta3 subunit), clone ab62 - 1996244 1996244
      Anti-LIBS2 epitope (Integrin beta3 subunit), clone ab62 - 2199673 2199673
      Anti-LIBS2 epitope (Integrin beta3 subunit), clone ab62 - 2275634 2275634
      Anti-LIBS2 epitope (Integrin beta3 subunit), clone ab62 - 2299594 2299594
      Anti-LIBS2 epitope (Integrin beta3 subunit), clone ab62 - 3180447 3180447
      Anti-LIBS2 epitope (Integrin beta3 subunit), clone ab62 - 3500964 3500964
      Anti-LIBS2 epitope (Integrin beta3 subunit), clone ab62 - 3697391 3697391
      Anti-LIBS2 epitope (Integrin beta3 subunit), clone ab62 - 3739736 3739736
      Anti-LIBS2 epitope (Integrin beta3 subunit), clone ab62 - 3894079 3894079
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