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203800 Adenosine 3ʹ,5ʹ-cyclic Monophosphate, 8-Bromo-, Sodium Salt - CAS 76939-46-3 - Calbiochem

Adenosine 3ʹ,5ʹ-cyclic Monophosphate, 8-Bromo-, Sodium Salt, CAS 76939-46-3, is a cell-permeable cAMP analog with greater resistance to phosphodiesterases. Preferentially activates protein kinase A.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 8-Bromo-cAMP, Na

Primary Target: PKA
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203800
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Overview

Key Spec Table

CAS #Empirical Formula
76939-46-3C₁₀H₁₀BrN₅O₆P · Na

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203800-10MG
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      Description
      OverviewCell-permeable cAMP analog that has greater resistance to phosphodiesterases than cAMP. Preferentially activates protein kinase A (PKA). Directly activates Epac, a Rap1 guanine-nucleotide exchange factor.
      Catalogue Number203800
      Brand Family Calbiochem®
      Synonyms8-Bromo-cAMP, Na
      References
      ReferencesKawasaki, H., et al. 1998. Science 282, 2275.
      de Rooij, J., et al. 1998. Nature 396, 474.
      Boyer, B., and Thiery, J.P. 1993. J. Cell Biol. 120, 767.
      Hei, Y.-J., et al. 1991. Mol. Pharmacol. 39, 233.
      Product Information
      CAS number76939-46-3
      ATP CompetitiveN
      FormWhite solid
      Hill FormulaC₁₀H₁₀BrN₅O₆P · Na
      Chemical formulaC₁₀H₁₀BrN₅O₆P · Na
      Hygroscopic Hygroscopic
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      ApplicationAdenosine 3ʹ,5ʹ-cyclic Monophosphate, 8-Bromo-, Sodium Salt, CAS 76939-46-3, is a cell-permeable cAMP analog with greater resistance to phosphodiesterases. Preferentially activates protein kinase A.
      Biological Information
      Primary TargetPKA
      Purity≥98% by HPLC
      Physicochemical Information
      Cell permeableY
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. Avoid pH >8.5.
      Global Trade Item Number
      Catalogue Number GTIN
      203800-10MG 04055977203998