566313 Sigma-AldrichSIRT1 Activator II - CAS 374922-43-7 - Calbiochem
The SIRT1 Activator II, also referenced under CAS 374922-43-7, modulates the biological activity of SIRT1. This small molecule/inhibitor is primarily used for Biochemicals applications.
More>> The SIRT1 Activator II, also referenced under CAS 374922-43-7, modulates the biological activity of SIRT1. This small molecule/inhibitor is primarily used for Biochemicals applications. Less<<SDB (Sicherheitsdatenblätter), Analysenzertifikate und Qualitätszertifikate, Dossiers, Broschüren und andere verfügbare Dokumente.
Synonyme: 3-(Benzenesulfonyl)-1-(4-fluorophenyl)pyrrolo[4,5-b]quinoxalin-2-amine , CAY10602, SIRT1 Activator II
Empfohlene Produkte
Übersicht
| Replacement Information |
|---|
Key Spec Table
| CAS # | Empirical Formula |
|---|---|
| 374922-43-7 | C₂₂H₁₅FN₄O₂S |
Preis & Verfügbarkeit
| Bestellnummer | Verfügbarkeit | Verpackung | St./Pkg. | Preis | Menge | |
|---|---|---|---|---|---|---|
| 566313-10MG |
|
Glasflasche | 10 mg |
|
— |
| Description | |
|---|---|
| Overview | A cell-permeable pyrroloquinoxaline compound that acts as a reversible SIRT1 activator (10 µM causes ~2.3-fold fluorescent enhancement in a fluorescent assay using hrSIRT1) and enhances fat mobilization in fully differentiated 3T3L1 fibroblasts. Shown to inhibit LPS-induced TNF-α release in THP-1 cells by ~10-fold more potent than resveratrol (Cat. No. 554325). |
| Catalogue Number | 566313 |
| Brand Family | Calbiochem® |
| Synonyms | 3-(Benzenesulfonyl)-1-(4-fluorophenyl)pyrrolo[4,5-b]quinoxalin-2-amine , CAY10602, SIRT1 Activator II |
| References | |
|---|---|
| References | Lavu, S., et al. 2008. Nat. Rev. Drug Discov. 7, 841. Nayagam, V.M., et al. 2006. J. Biomol. Screen. 11, 959. |
| Product Information | |
|---|---|
| CAS number | 374922-43-7 |
| Form | Off-white powder |
| Hill Formula | C₂₂H₁₅FN₄O₂S |
| Chemical formula | C₂₂H₁₅FN₄O₂S |
| Structure formula Image | |
| Quality Level | MQ100 |
| Applications |
|---|
| Biological Information | |
|---|---|
| Purity | ≥98% by HPLC |
| Physicochemical Information |
|---|
| Dimensions |
|---|
| Materials Information |
|---|
| Toxicological Information |
|---|
| Safety Information according to GHS |
|---|
| Safety Information |
|---|
| Product Usage Statements |
|---|
| Packaging Information | |
|---|---|
| Packaged under inert gas | Packaged under inert gas |
| Transport Information |
|---|
| Supplemental Information |
|---|
| Specifications |
|---|
| Global Trade Item Number | |
|---|---|
| Bestellnummer | GTIN |
| 566313-10MG | 04055977191363 |
Documentation
SIRT1 Activator II - CAS 374922-43-7 - Calbiochem SDB
| Titel |
|---|
SIRT1 Activator II - CAS 374922-43-7 - Calbiochem Analysenzertifikate
| Titel | Chargennummer |
|---|---|
| 566313 |
Literatur
| Übersicht |
|---|
| Lavu, S., et al. 2008. Nat. Rev. Drug Discov. 7, 841. Nayagam, V.M., et al. 2006. J. Biomol. Screen. 11, 959. |
| Datenblatt | ||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
|