516481 Sigma-AldrichPepstatin A, Synthetic - CAS 26305-03-3 - Calbiochem
Pepstatin A, Synthetic, CAS 26305-03-3, is a reversible inhibitor of aspartic proteases. Inhibits cathepsin D, pepsin, and renin.
More>> Pepstatin A, Synthetic, CAS 26305-03-3, is a reversible inhibitor of aspartic proteases. Inhibits cathepsin D, pepsin, and renin. Less<<SDB (Sicherheitsdatenblätter), Analysenzertifikate und Qualitätszertifikate, Dossiers, Broschüren und andere verfügbare Dokumente.
Synonyme: Iva-Val-Val-Sta-Ala-Sta, Isovaleryl-Val-Val-4-amino-3-hydroxy-6-methylheptanoyl-Ala-4-amino-3-hydroxy-6-methylheptanoic Acid
Empfohlene Produkte
Übersicht
| Replacement Information |
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Key Spec Table
| CAS # | Empirical Formula |
|---|---|
| 26305-03-3 | C₃₄H₆₃N₅O₉ |
Preis & Verfügbarkeit
| Bestellnummer | Verfügbarkeit | Verpackung | St./Pkg. | Preis | Menge | |
|---|---|---|---|---|---|---|
| 516481-100MG |
|
Kst.-Ampulle | 100 mg |
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| 516481-25MG |
|
Kst.-Ampulle | 25 mg |
|
— | |
| 516481-5MG |
|
Kst.-Ampulle | 5 mg |
|
— |
| Description | |
|---|---|
| Overview | A reversible inhibitor of aspartic proteases. Inhibits cathepsin D, pepsin, and renin. Reported to block apoptosis induced by CA-074 (Cat. No. 205530) in PC12 cell lines. Also available as a 25 mM solution in DMSO (Cat. No. 508437). |
| Effective concentration: 1.0 µM. | |
| Catalogue Number | 516481 |
| Brand Family | Calbiochem® |
| Synonyms | Iva-Val-Val-Sta-Ala-Sta, Isovaleryl-Val-Val-4-amino-3-hydroxy-6-methylheptanoyl-Ala-4-amino-3-hydroxy-6-methylheptanoic Acid |
| Product Information | |
|---|---|
| CAS number | 26305-03-3 |
| ATP Competitive | N |
| Form | White solid |
| Hill Formula | C₃₄H₆₃N₅O₉ |
| Chemical formula | C₃₄H₆₃N₅O₉ |
| Optical rotation | Optical rotation: -90.0 ± 5° (c = 0.5, MeOH, 20°C). |
| Reversible | Y |
| Quality Level | MQ100 |
| Applications |
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| Biological Information | |
|---|---|
| Primary Target | cathepsin D |
| Primary Target IC<sub>50</sub> | EC50 = 1.0 µM in blocking apoptosis induced by CA-074 in PC12 cell lines |
| Purity | ≥98% by HPLC |
| Physicochemical Information | |
|---|---|
| Cell permeable | N |
| Dimensions |
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| Materials Information |
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| Toxicological Information |
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| Safety Information according to GHS | |
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| RTECS | SC6155000 |
| Safety Information |
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| Product Usage Statements |
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| Packaging Information |
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| Transport Information |
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| Supplemental Information |
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| Specifications |
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| Global Trade Item Number | |
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| Bestellnummer | GTIN |
| 516481-100MG | 04055977198812 |
| 516481-25MG | 07790788055837 |
| 516481-5MG | 04055977198836 |
Documentation
Pepstatin A, Synthetic - CAS 26305-03-3 - Calbiochem SDB
| Titel |
|---|
Pepstatin A, Synthetic - CAS 26305-03-3 - Calbiochem Analysenzertifikate
| Titel | Chargennummer |
|---|---|
| 516481 |
Literatur
| Übersicht |
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| Isahara, K., et al. 1999. Neuroscience 91, 233. Kanamori, S., et al. 1998. Biochem. Biophys. Res. Commun. 251, 204. Szewczuk, Z., et al. 1992. Int. J. Pept. Prot. Res. 40, 233. Carraway, R.E., et al. 1991. Peptides 12, 107. Eid, M., et al. 1981. Biochem. J. 197, 465. Umezawa, H., et al. 1970. J. Antibiot. 23, 259. |
Broschüre
| Titel |
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| Western Blotting Tools |
Technische Informationen
| Titel |
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| Protein Blotting Handbook: 6th Edition |