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504359 Palmitoylethanolamide - CAS 544-31-0 - Calbiochem

Palmitoylethanolamide is an endogenous lipid that acts as a selective agonist for GPR55 receptors. Producing robust anti-inflammatory actions by activating PPARα (EC₅₀ = 3 µM).

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Synonyme: N-(2-Hydroxyethyl)hexadecanamide, PEA, Palmidrol

Primary Target: GPR55 receptor
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504359
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Übersicht

Replacement Information

Key Spec Table

CAS #Empirical Formula
544-31-0C₁₈H₃₇NO₂

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      Description
      OverviewAn endogenous lipid that acts as a selective agonist for GPR55 receptors (EC50 = 4, 19 800 and > 30 000 nM at GPR55, CB2 and CB1 receptors respectively). Producing robust anti-inflammatory actions by activating PPARα (EC50 = 3 µM).
      Catalogue Number504359
      Brand Family Calbiochem®
      SynonymsN-(2-Hydroxyethyl)hexadecanamide, PEA, Palmidrol
      References
      ReferencesGriffin, G., et al. 2000. J. Pharmacol. Exp. Ther. 292, 886.
      Lambert, D., et al. 2001. Epilepsia. 42, 321.
      Lambert, D., et al. 2002. Curr. Med. Chem. 9, 663.
      Lo Verme, J., et al. 2005. Life Sci. 77, 1685.
      Re, G., et al. 2005. Vet. J. 173, 21.
      Ryberg, R., et al. 2007. Br. J. Pharmacol. 152, 1092.
      Product Information
      CAS number544-31-0
      FormWhite solid
      Hill FormulaC₁₈H₃₇NO₂
      Chemical formulaC₁₈H₃₇NO₂
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetGPR55 receptor
      Purity≥99% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Bestellnummer GTIN
      5043590001 04055977263978

      Documentation

      Palmitoylethanolamide - CAS 544-31-0 - Calbiochem SDB

      Titel

      Sicherheitsdatenblatt (SDB) 

      Palmitoylethanolamide - CAS 544-31-0 - Calbiochem Analysenzertifikate

      TitelChargennummer
      504359

      Literatur

      Übersicht
      Griffin, G., et al. 2000. J. Pharmacol. Exp. Ther. 292, 886.
      Lambert, D., et al. 2001. Epilepsia. 42, 321.
      Lambert, D., et al. 2002. Curr. Med. Chem. 9, 663.
      Lo Verme, J., et al. 2005. Life Sci. 77, 1685.
      Re, G., et al. 2005. Vet. J. 173, 21.
      Ryberg, R., et al. 2007. Br. J. Pharmacol. 152, 1092.
      Datenblatt

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision12-July-2013 JSW
      SynonymsN-(2-Hydroxyethyl)hexadecanamide, PEA, Palmidrol
      DescriptionAn endogenous lipid that acts as a selective agonist for GPR55 receptors (EC50 = 4, 19 800 and > 30 000 nM at GPR55, CB2 and CB1 receptors respectively). Producing robust anti-inflammatory actions by activating PPARα (EC50 = 3 µM).
      FormWhite solid
      CAS number544-31-0
      Chemical formulaC₁₈H₃₇NO₂
      Structure formulaStructure formula
      Purity≥99% by HPLC
      SolubilityDMSO (20 mM). Slight warming is required for complete solubilization.
      Storage Protect from light
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesGriffin, G., et al. 2000. J. Pharmacol. Exp. Ther. 292, 886.
      Lambert, D., et al. 2001. Epilepsia. 42, 321.
      Lambert, D., et al. 2002. Curr. Med. Chem. 9, 663.
      Lo Verme, J., et al. 2005. Life Sci. 77, 1685.
      Re, G., et al. 2005. Vet. J. 173, 21.
      Ryberg, R., et al. 2007. Br. J. Pharmacol. 152, 1092.