513040 Sigma-AldrichPD 174265 - CAS 216163-53-0 - Calbiochem
A potent, cell-permeable, reversible, ATP-competitive and selective inhibitor of EGF receptor (EGFR) tyrosine kinase activity (IC₅₀ = 450 pM).
More>> A potent, cell-permeable, reversible, ATP-competitive and selective inhibitor of EGF receptor (EGFR) tyrosine kinase activity (IC₅₀ = 450 pM). Less<<PD 174265 - CAS 216163-53-0 - Calbiochem: SDB (Sicherheitsdatenblätter), Analysenzertifikate und Qualitätszertifikate, Dossiers, Broschüren und andere verfügbare Dokumente.
Synonyme: 4-[(3-Bromophenyl)amino]-6-propionylamidoquinazoline
Empfohlene Produkte
Übersicht
| Replacement Information |
|---|
Key Spec Table
| CAS # | Empirical Formula |
|---|---|
| 216163-53-0 | C₁₇H₁₅BrN₄O |
Preis & Verfügbarkeit
| Bestellnummer | Verfügbarkeit | Verpackung | St./Pkg. | Preis | Menge | |
|---|---|---|---|---|---|---|
| 513040-1MG |
|
Kst.-Ampulle | 1 mg |
|
— |
| Description | |
|---|---|
| Overview | A potent, cell-permeable, reversible, ATP-competitive and selective inhibitor of EGF receptor (EGFR) tyrosine kinase activity (IC50 = 450 pM). The reversible nature of this compound makes it a less effective antitumor agent than PD 168393 (Cat. No. 513033). |
| Catalogue Number | 513040 |
| Brand Family | Calbiochem® |
| Synonyms | 4-[(3-Bromophenyl)amino]-6-propionylamidoquinazoline |
| References | |
|---|---|
| References | Fry, D.W., et al. 1998. Proc. Natl. Acad. Sci. USA 95, 12022. |
| Product Information | |
|---|---|
| CAS number | 216163-53-0 |
| ATP Competitive | Y |
| Form | Yellow solid |
| Hill Formula | C₁₇H₁₅BrN₄O |
| Chemical formula | C₁₇H₁₅BrN₄O |
| Reversible | Y |
| Structure formula Image | |
| Quality Level | MQ100 |
| Applications |
|---|
| Biological Information | |
|---|---|
| Primary Target | EGFR tyrosine kinase activity |
| Primary Target IC<sub>50</sub> | 450 pM against EGF receptor (EGFR) tyrosine kinase activity |
| Purity | ≥97% by HPLC |
| Physicochemical Information | |
|---|---|
| Cell permeable | Y |
| Dimensions |
|---|
| Materials Information |
|---|
| Toxicological Information |
|---|
| Safety Information according to GHS |
|---|
| Safety Information |
|---|
| Product Usage Statements |
|---|
| Packaging Information | |
|---|---|
| Packaged under inert gas | Packaged under inert gas |
| Transport Information |
|---|
| Supplemental Information |
|---|
| Specifications |
|---|
| Global Trade Item Number | |
|---|---|
| Bestellnummer | GTIN |
| 513040-1MG | 04055977198669 |
Documentation
PD 174265 - CAS 216163-53-0 - Calbiochem SDB
| Titel |
|---|
PD 174265 - CAS 216163-53-0 - Calbiochem Analysenzertifikate
| Titel | Chargennummer |
|---|---|
| 513040 |
Literatur
| Übersicht |
|---|
| Fry, D.W., et al. 1998. Proc. Natl. Acad. Sci. USA 95, 12022. |