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444218 MMP-3 Inhibitor I - Calbiochem

The MMP-3 Inhibitor I controls the biological activity of MMP-3. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

MMP-3 Inhibitor I - Calbiochem: SDB (Sicherheitsdatenblätter), Analysenzertifikate und Qualitätszertifikate, Dossiers, Broschüren und andere verfügbare Dokumente.

Synonyme: Ac-RCGVPD-NH₂, Stromelysin-1 Inhibitor

Primary Target: MMP-3
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444218
Preis & Verfügbarkeit

Übersicht

Replacement Information

Key Spec Table

Empirical Formula
C₂₇H₄₆N₁₀O₉S

Preis & Verfügbarkeit

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444218-5MG
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      		 Kst.-Ampulle 5 mg
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      Description
      OverviewInhibits the matrix metalloproteinase MMP-3 (IC50 = 5 µM).
      Catalogue Number444218
      Brand Family Calbiochem®
      SynonymsAc-RCGVPD-NH₂, Stromelysin-1 Inhibitor
      References
      ReferencesFotouhi, N., et al. 1994. J. Biol. Chem. 269, 30227.
      Hanglow, A.C., et al. 1993. Agents Actions 39, C148.
      Product Information
      ATP CompetitiveN
      FormWhite solid
      FormulationSupplied as a trifluroacetate salt.
      Hill FormulaC₂₇H₄₆N₁₀O₉S
      Chemical formulaC₂₇H₄₆N₁₀O₉S
      Hygroscopic Hygroscopic
      ReversibleN
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetMMP-3
      Primary Target IC<sub>50</sub>5 µM against MMP-3
      Purity≥90% by HPLC
      Physicochemical Information
      Cell permeableN
      Peptide SequenceAc-Arg-Cys-Gly-Val-Pro-Asp-NH₂
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing recosntitution, aliquot and freeze (-20°C). Stock solutions are stable for 1-2 weeks at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Bestellnummer GTIN
      444218-5MG 04055977205220

      Documentation

      MMP-3 Inhibitor I - Calbiochem SDB

      Titel

      Sicherheitsdatenblatt (SDB) 

      MMP-3 Inhibitor I - Calbiochem Analysenzertifikate

      TitelChargennummer
      444218

      Literatur

      Übersicht
      Fotouhi, N., et al. 1994. J. Biol. Chem. 269, 30227.
      Hanglow, A.C., et al. 1993. Agents Actions 39, C148.

      Literaturstellen

      Titel
    • Anthony R. White, et al. (2006) Degradation of the alzheimer disease amyloid -peptide by metal-dependent up-regulation of metalloprotease activity. journal of Biological Chemistry 281, 17670-17680.
      		•
      Datenblatt

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision31-January-2008 JSW
      SynonymsAc-RCGVPD-NH₂, Stromelysin-1 Inhibitor
      DescriptionInhibits matrix metalloproteinase-3 (stromelysin) (IC50 = 5 µM). The inhibitor is based on a segment from the conserved region of the NH2-terminal propeptide domain.
      FormWhite solid
      FormulationSupplied as a trifluroacetate salt.
      Chemical formulaC₂₇H₄₆N₁₀O₉S
      Peptide SequenceAc-Arg-Cys-Gly-Val-Pro-Asp-NH₂
      Purity≥90% by HPLC
      SolubilityH₂O (1 mg/ml)
      Storage -20°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing recosntitution, aliquot and freeze (-20°C). Stock solutions are stable for 1-2 weeks at -20°C.
      Toxicity Standard Handling
      ReferencesFotouhi, N., et al. 1994. J. Biol. Chem. 269, 30227.
      Hanglow, A.C., et al. 1993. Agents Actions 39, C148.
      Citation
    • Anthony R. White, et al. (2006) Degradation of the alzheimer disease amyloid -peptide by metal-dependent up-regulation of metalloprotease activity. journal of Biological Chemistry 281, 17670-17680.
      		•

      Verwandte Produkte & Anwendungen

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      Bestellnummer Beschreibung  
      444225 MMP-3 Inhibitor II - CAS 161314-17-6 - Calbiochem Preis & Verfügbarkeit

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      444217 MMP-3, Catalytic Domain, Human, Recombinant, E. coli Preis & Verfügbarkeit

      Kategorien

      Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Proteases Inhibitors > Matrix Metalloproteinase (MMP) Inhibitors