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444241 MMP-2/MMP-9 Inhibitor I - CAS 193807-58-8 - Calbiochem

The MMP-2/MMP-9 Inhibitor I, also referenced under CAS 193807-58-8, controls the biological activity of MMP-2/MMP-9. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

SDB (Sicherheitsdatenblätter), Analysenzertifikate und Qualitätszertifikate, Dossiers, Broschüren und andere verfügbare Dokumente.

Synonyme: (2R)-2-[(4-Biphenylylsulfonyl)amino]-3-phenylpropionic Acid

Primary Target: MMP-2, MMP-9
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444241
Preis & Verfügbarkeit

Übersicht

Replacement Information

Key Spec Table

CAS #Empirical Formula
193807-58-8C₂₁H₁₉NO₄S

Preis & Verfügbarkeit

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444241-5MG
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      		 Kst.-Ampulle 5 mg
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      Description
      OverviewA potent inhibitor of MMP-2 (IC50 = 310 nM) and MMP-9 (IC50 = 240 nM). Orally active in animal models of tumor growth and metastasis.
      Catalogue Number444241
      Brand Family Calbiochem®
      Synonyms(2R)-2-[(4-Biphenylylsulfonyl)amino]-3-phenylpropionic Acid
      References
      ReferencesTamura, Y., et al. 1998. J. Med. Chem. 41, 640.
      Product Information
      CAS number193807-58-8
      ATP CompetitiveN
      FormWhite solid
      Hill FormulaC₂₁H₁₉NO₄S
      Chemical formulaC₂₁H₁₉NO₄S
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetMMP-2, MMP-9
      Primary Target IC<sub>50</sub>310 nM and 240 nM against MMP-2 and MMP-9
      Purity≥95% by HPLC
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Bestellnummer GTIN
      444241-5MG 07790788056384

      Documentation

      MMP-2/MMP-9 Inhibitor I - CAS 193807-58-8 - Calbiochem SDB

      Titel

      Sicherheitsdatenblatt (SDB) 

      MMP-2/MMP-9 Inhibitor I - CAS 193807-58-8 - Calbiochem Analysenzertifikate

      TitelChargennummer
      444241

      Literatur

      Übersicht
      Tamura, Y., et al. 1998. J. Med. Chem. 41, 640.
      Datenblatt

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision01-April-2011 RFH
      Synonyms(2R)-2-[(4-Biphenylylsulfonyl)amino]-3-phenylpropionic Acid
      DescriptionA potent inhibitor of MMP-2 (gelatinase A; IC50 = 310 nM) and MMP-9 (gelatinase B; IC50 = 240 nM).
      FormWhite solid
      Intert gas (Yes/No) Packaged under inert gas
      CAS number193807-58-8
      Chemical formulaC₂₁H₁₉NO₄S
      Structure formulaStructure formula
      Purity≥95% by HPLC
      SolubilityDMSO (200 mg/ml)
      Storage -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Toxicity Standard Handling
      ReferencesTamura, Y., et al. 1998. J. Med. Chem. 41, 640.