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12-420 Long S6 Kinase Substrate Peptide

Long S6 Kinase Substrate Peptide: SDB (Sicherheitsdatenblätter), Analysenzertifikate und Qualitätszertifikate, Dossiers, Broschüren und andere verfügbare Dokumente.
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12-420
1 mg  
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      Übersicht

      Replacement Information
      Description
      Catalogue Number12-420
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionLong S6 Kinase Substrate Peptide
      References
      Product Information
      PresentationLyophilized
      Quality LevelMQ100
      Applications
      Key Applications
      • Kinase Assay
      Biological Information
      Entrez Gene Number
      Entrez Gene SummaryThis gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
      Gene Symbol
      • RPS6KA1
      • pp90RSK1
      • HU-1
      • RSK-1
      • MAPKAPK1A
      • p90S6K
      • RSK1
      • RSK
      Protein Targetp70S6K
      Target Sub-FamilyAGC
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: Q15418 # Serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB.
      COFACTOR: Magnesium.
      SIZE: 735 amino acids; 82723 Da
      SUBUNIT: Forms a complex with either ERK1 or ERK2 in quiescent cells. Transiently dissociates following mitogenic stimulation.
      PTM: Autophosphorylated on Ser-380, as part of the activation process.
      SIMILARITY: SwissProt: Q15418 ## Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. & Contains 1 AGC-kinase C-terminal domain. & Contains 2 protein kinase domains.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceRoutinely evaluated as a substrate for ROK (Catalogue No. 14-338) and other kinases.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage Conditions2 years at 4°C
      Packaging Information
      Material Size1 mg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Bestellnummer GTIN
      12-420 04053252372988

      Documentation

      Long S6 Kinase Substrate Peptide SDB

      Titel

      Sicherheitsdatenblatt (SDB) 

      Long S6 Kinase Substrate Peptide Analysenzertifikate

      TitelChargennummer
      Long S6 Kinase Substrate Peptide 2959010
      Long S6 Kinase Substrate Peptide 2928462
      Long S6 Kinase Substrate Peptide 2970719
      Long S6 Kinase Substrate Peptide 3089178
      Long S6 Kinase Substrate Peptide 3046207
      Long S6 Kinase Substrate Peptide 3028347
      Long S6 Kinase Substrate Peptide - 1947714 1947714
      Long S6 Kinase Substrate Peptide - 2026379 2026379
      Long S6 Kinase Substrate Peptide - 20298 20298
      Long S6 Kinase Substrate Peptide - 23236 23236
      Show more

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      Kategorien

      Life Science Research > Proteins and Enzymes > Substrate & Control Proteins > Kinase & Phosphatase Substrates
      Life Science Research > Drug Discovery and Development > Kinase & Phosphatase Screening > Kinase & Phosphatase Substrates