508158 Sigma-AldrichInSolution™ TGF-β RI Kinase Inhibitor II, RepSox - CAS 446859-33-2 - Calbiochem
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Primary Target:
ALK5
SDB (Sicherheitsdatenblätter), Analysenzertifikate und Qualitätszertifikate, Dossiers, Broschüren und andere verfügbare Dokumente.
Synonyme: 2-(3-(6-Methylpyridin-2-yl)-1H-pyrazol-4-yl)-1,5-naphthyridine, RepSox InSolution, E-616452 InSolution, ALK5 Inhibitor II, Transforming Growth Factor-β, Type I Receptor Kinase Inhibitor II
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Übersicht
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Key Spec Table
| CAS # | Empirical Formula |
|---|---|
| 446859-33-2 | C₁₇H₁₃N₅ |
Preis & Verfügbarkeit
| Bestellnummer | Verfügbarkeit | Verpackung | St./Pkg. | Preis | Menge | |
|---|---|---|---|---|---|---|
| 5081580001 |
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Glasflasche | 5 mg |
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| References | |
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| References | Ichida, J. K., et al. 2009. Cell Stem Cell 5, 491. Gellibert, F., et al. 2004. J. Med. Chem. 47, 4494. |
| Product Information | |
|---|---|
| CAS number | 446859-33-2 |
| Form | Liquid |
| Formulation | A 50 mM (5 mg/348 µl) sterile-filtered solution of TGF-β RI Kinase Inhibitor II, RepSox (Cat. No. 616452) in DMSO. |
| Hill Formula | C₁₇H₁₃N₅ |
| Chemical formula | C₁₇H₁₃N₅ |
| Hygroscopic | Hygroscopic |
| Reversible | Y |
| Structure formula Image | |
| Quality Level | MQ100 |
| Applications |
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| Biological Information | |
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| Primary Target | ALK5 |
| Primary Target IC<sub>50</sub> | 23 nM, 4 nM and 18 nM for ALK5 binding, ALK5 auto-phosphorylation, and TGF-&beta |
| Purity | ≥99% by HPLC |
| Physicochemical Information | |
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| Cell permeable | Y |
| Dimensions |
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| Materials Information |
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| Toxicological Information |
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| Safety Information according to GHS |
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| Safety Information |
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| Product Usage Statements |
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| Packaging Information | |
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| Packaged under inert gas | Packaged under inert gas |
| Transport Information |
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| Supplemental Information |
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| Specifications |
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| Global Trade Item Number | |
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| Bestellnummer | GTIN |
| 5081580001 | 04055977242904 |
Documentation
InSolution™ TGF-β RI Kinase Inhibitor II, RepSox - CAS 446859-33-2 - Calbiochem SDB
| Titel |
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Literatur
| Übersicht |
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| Ichida, J. K., et al. 2009. Cell Stem Cell 5, 491. Gellibert, F., et al. 2004. J. Med. Chem. 47, 4494. |
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Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
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