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GF328 IL-17,
Human Recombinant Animal Free

IL-17,
Human Recombinant Animal Free: SDB (Sicherheitsdatenblätter), Analysenzertifikate und Qualitätszertifikate, Dossiers, Broschüren und andere verfügbare Dokumente.
UniProt Number: Q16552
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GF328
25µg  
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      Übersicht

      Replacement Information

      Key Spec Table

      SourcePurity
      Protein is expressed in E.coli.
      The protein is manufactured without the use of any animal products/reagents and is considered Animal-Free and can be used in protocols where possible transmisson of animal viruses and contamination must be avoided.      		Product endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
      Description
      Catalogue NumberGF328
      DescriptionIL-17,
      Human Recombinant Animal Free
      Alternate Names
      • Interleukin-17
      • IL17
      • IL17a
      Background InformationThe originally described IL-17 protein, now known as IL-17A, is a homodimer of two 136 amino acid chains, secreted by activated T-cells that act on stromal cells to induce production of proinflammatory and hematopoietic bioactive molecules. Today, IL-17 represents a family of structurally-related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17A exhibits cross-species bioactivity between human and murine cells.
      Recombinant human IL-17A is a 31.3 kDa disulfide-linked homodimer of two 137 amino acid polypeptide chains.
      References
      Product Information
      PresentationProduct is presented without additives and is filtered through a 0.2 micron filter before lyophilization.
      Quality LevelMQ100
      Applications
      Biological Information
      PurityProduct endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
      SourceProtein is expressed in E.coli.
      The protein is manufactured without the use of any animal products/reagents and is considered Animal-Free and can be used in protocols where possible transmisson of animal viruses and contamination must be avoided.
      UniProt Number
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceAssay #1: Determined by the dosedependent induction of IL-6 in primary human foreskin fibroblast. The expected ED50 is ≤ 2.0 ng/ml, corresponding to a specific activity of ≥ 5 x 10^5 units/mg.
      Assay #2: Measured by its ability to induce IL-6 production by NHDF cells.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStore at -20°C for up to 4 months from date of receipt Centrifuge the vial prior to opening.
      Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein and store in working aliquots at -20°C.
      Packaging Information
      Material Size25µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Bestellnummer GTIN
      GF328 04053252978913

      Documentation

      IL-17,
      Human Recombinant Animal Free SDB

      Titel

      Sicherheitsdatenblatt (SDB) 

      IL-17,
      Human Recombinant Animal Free Analysenzertifikate

      TitelChargennummer
      IL-17, Human Recombinant Animal Free - Q2442614 Q2442614
      IL-17, Human Recombinant Animal Free - 3279693 3279693
      IL-17, Human Recombinant Animal Free - 3532078 3532078
      IL-17, Human Recombinant Animal Free - 3743853 3743853
      IL-17, Human Recombinant Animal Free - 3755333 3755333
      IL-17, Human Recombinant Animal Free - 3894061 3894061
      IL-17, Human Recombinant Animal Free - 4002907 4002907
      IL-17, Human Recombinant Animal Free Recombinant Protein 2951392

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      Kategorien

      Life Science Research > Proteins and Enzymes > Cytokines & Growth Factors
      Life Science Research > Cell Culture and Systems > Cell Culture Media and Supplements > Cell Culture Supplements > Cytokines & Growth Factors