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513100 DL-threo-PDMP, Hydrochloride - CAS 80938-69-8 - Calbiochem

PDMP closely resembles the natural sphingolipid substrate of brain glucosyltransferase and acts as a potent and competitive inhibitor of this enzyme.

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Synonyme: 1-Phenyl-2-decanoylamino-3-morpholino-1-propanol, HCl

Primary Target: glycolipid synthesis in cultured NIH/3T3 cells
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513100
Preis & Verfügbarkeit

Übersicht

Replacement Information

Key Spec Table

CAS #Empirical Formula
80938-69-8C₂₃H₃₈N₂O₃ · HCl

Preis & Verfügbarkeit

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513100-50MG
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      Description
      OverviewPDMP closely resembles the natural sphingolipid substrate of brain glucosyltransferase and acts as a potent and competitive inhibitor of this enzyme. Blocks the outgrowth of neurites and inhibits glycolipid synthesis in cultured NIH/3T3 cells.
      Catalogue Number513100
      Brand Family Calbiochem®
      Synonyms1-Phenyl-2-decanoylamino-3-morpholino-1-propanol, HCl
      References
      ReferencesRani, C.S., et al. 1995. J. Biol. Chem. 270, 2859.
      Rosenwald, A.G. 1992. Biochemistry 31, 3581.
      Inokuchi, J., and Radin, N.S. 1987. J. Lipid Res. 28, 565.
      Vunnam, R.R., and Radin, N.S. 1980. Chem. Phys. Lipids 26, 265.
      Product Information
      CAS number80938-69-8
      ATP CompetitiveN
      FormWhite solid
      Hill FormulaC₂₃H₃₈N₂O₃ · HCl
      Chemical formulaC₂₃H₃₈N₂O₃ · HCl
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary Targetglycolipid synthesis in cultured NIH/3T3 cells
      Purity≥98% by HPLC
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      R PhraseR: 36/37/38

      Irritating to eyes, respiratory system and skin.
      S PhraseS: 26-36

      In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
      Wear suitable protective clothing.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Irritant
      Storage -20°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. Avoid freeze/thaw cycles of solutions.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Bestellnummer GTIN
      513100-50MG 04055977198683

      Documentation

      DL-threo-PDMP, Hydrochloride - CAS 80938-69-8 - Calbiochem SDB

      Titel

      Sicherheitsdatenblatt (SDB) 

      DL-threo-PDMP, Hydrochloride - CAS 80938-69-8 - Calbiochem Analysenzertifikate

      TitelChargennummer
      513100

      Literatur

      Übersicht
      Rani, C.S., et al. 1995. J. Biol. Chem. 270, 2859.
      Rosenwald, A.G. 1992. Biochemistry 31, 3581.
      Inokuchi, J., and Radin, N.S. 1987. J. Lipid Res. 28, 565.
      Vunnam, R.R., and Radin, N.S. 1980. Chem. Phys. Lipids 26, 265.
      Datenblatt

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision06-October-2023 JSW
      Synonyms1-Phenyl-2-decanoylamino-3-morpholino-1-propanol, HCl
      DescriptionPDMP closely resembles the natural sphingolipid substrate of brain glucosyltransferase and is a potent and competitive inhibitor of this enzyme. Blocks the outgrowth of neurites and inhibits glycolipid synthesis in cultured 3T3 cells.
      FormWhite solid
      CAS number80938-69-8
      Chemical formulaC₂₃H₃₈N₂O₃ · HCl
      Structure formulaStructure formula
      Purity≥98% by HPLC
      SolubilityDMSO, methanol, or ethanol
      Storage -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. Avoid freeze/thaw cycles of solutions.
      Toxicity Irritant
      ReferencesRani, C.S., et al. 1995. J. Biol. Chem. 270, 2859.
      Rosenwald, A.G. 1992. Biochemistry 31, 3581.
      Inokuchi, J., and Radin, N.S. 1987. J. Lipid Res. 28, 565.
      Vunnam, R.R., and Radin, N.S. 1980. Chem. Phys. Lipids 26, 265.