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14-917M CLK4 Protein, active, 250 µg

Active, N-terminal 6His-tagged, recombinant, human CLK4, amino acids 128-end, for use in Kinase Assays.

CLK4 Protein, active, 250 µg: SDB (Sicherheitsdatenblätter), Analysenzertifikate und Qualitätszertifikate, Dossiers, Broschüren und andere verfügbare Dokumente.
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14-917M
250 µg  Also available in 10μg size as catalog # 14-917 and in bulk as catalog # 14-917-K.
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      Übersicht

      Replacement Information
      Description
      Catalogue Number14-917M
      Trade Name
      • Upstate
      DescriptionCLK4 Protein, active, 250 µg
      OverviewCLK4 protein belongs to the CDC2-like protein kinase (CLK) family. This protein kinase can interact with and phosphorylate the serine- and arginine-rich (SR) proteins, which are known to play an important role in the formation of spliceosomes, and thus may be involved in the regulation of alternative splicing. Studies in the Israeli sand rat Psammomys obesus suggested that the ubiquitin-like 5 (UBL5/BEACON), a highly conserved ubiquitin-like protein, may interact with and regulate the activity of this kinase. Multiple alternatively spliced transcript variants have been observed, but the full-length natures of which have not yet been determined.
      References
      Product Information
      Presentation50mM Tris/HCl pH7.5, 300mM NaCl, 0.1mM EGTA, 0.03% Brij-35, 270mM sucrose, 1mM benzamidine, 0.2mM PMSF, 0.1% 2-mercaptoethanol.
      Quality LevelMQ300
      Applications
      ApplicationActive, N-terminal 6His-tagged, recombinant, human CLK4, amino acids 128-end, for use in Kinase Assays.
      Key Applications
      • Kinase Assay
      Biological Information
      SourceN-terminal 6His-tagged, recombinant, human CLK4 amino acids 128-end expressed by baculovirus in Sf21 insect cells.
      Specific ActivityFor Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
      Entrez Gene Number
      Gene Symbol
      • CLK4
      Protein TargetCLK4
      Purification MethodPurified using immobilized metal affinity chromatography.
      Target Sub-FamilyCMGC
      UniProt Number
      Molecular Weight46 kDa
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceRoutinely evaluated by phosphorylation of peptide YRRAAVPPSPSLSRHSSPHQS(p)EDEEE.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage Conditions6 months at -70°C
      Packaging Information
      Material Size250 µg
      Material PackageAlso available in 10μg size as catalog # 14-917 and in bulk as catalog # 14-917-K.
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Bestellnummer GTIN
      14-917M 04053252832123

      Verwandte Produkte & Anwendungen

      Alternative Packsize

      Bestellnummer Beschreibung  
      14-917 CLK4 Protein, active, 10 µg Preis & Verfügbarkeit

      Produktfamilien

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      Kategorien

      Life Science Research > Proteins and Enzymes > Purified Kinases
      Life Science Research > Drug Discovery and Development > Kinase & Phosphatase Screening > Purified Kinases