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200484 Bestatin - CAS 58970-76-6 - Calbiochem

Bestatin, CAS 58970-76-6, is a potent inhibitor of surface aminopeptidases, notably aminopeptidase B, N, and leucine aminopeptidase. Activates macrophages and T lymphocytes.

Bestatin - CAS 58970-76-6 - Calbiochem: SDB (Sicherheitsdatenblätter), Analysenzertifikate und Qualitätszertifikate, Dossiers, Broschüren und andere verfügbare Dokumente.

Synonyme: [(2S,3R)-3-Amino-2-hydroxy-4-phenylbutanoyl]-Leu

Primary Target: amino peptidase b
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200484
Preis & Verfügbarkeit

Übersicht

Replacement Information

Key Spec Table

CAS #Empirical Formula
58970-76-6C₁₆H₂₄N₂O₄

Preis & Verfügbarkeit

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200484-10MG
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      		 Kst.-Ampulle 10 mg
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      Description
      OverviewBinds to cell surfaces and inhibits surface aminopeptidases, notably aminopeptidase B and leucine aminopeptidase. Also acts as a potent aminopeptidase N inhibitor. Activates macrophages and T lymphocytes. Has antitumor properties. Also available as a 50 mM solution in water (Cat. No. 200488).
      Catalogue Number200484
      Brand Family Calbiochem®
      Synonyms[(2S,3R)-3-Amino-2-hydroxy-4-phenylbutanoyl]-Leu
      References
      ReferencesInoue, T., et al. 1994. J. Clin. Endocrinol. Metab. 79, 171.
      Taylor, A., et al. 1993. Biochemistry 32, 784.
      Ishida, J.I., et al. 1984. J. Chromatogr. 305, 381.
      Umezawa, H. 1982. Annu. Rev. Microbiol. 36, 75.
      Product Information
      CAS number58970-76-6
      ATP CompetitiveN
      FormWhite crystalline solid
      Hill FormulaC₁₆H₂₄N₂O₄
      Chemical formulaC₁₆H₂₄N₂O₄
      ReversibleN
      Quality LevelMQ100
      Applications
      ApplicationBestatin, CAS 58970-76-6, is a potent inhibitor of surface aminopeptidases, notably aminopeptidase B, N, and leucine aminopeptidase. Activates macrophages and T lymphocytes.
      Biological Information
      Primary Targetamino peptidase b
      Purity>99% by HPLC
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      RTECSOH2915000
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). DMSO and methanol stock solutions are stable for up to 1 month at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Bestellnummer GTIN
      200484-10MG 04055977221459

      Documentation

      Bestatin - CAS 58970-76-6 - Calbiochem SDB

      Titel

      Sicherheitsdatenblatt (SDB) 

      Bestatin - CAS 58970-76-6 - Calbiochem Analysenzertifikate

      TitelChargennummer
      200484

      Literatur

      Übersicht
      Inoue, T., et al. 1994. J. Clin. Endocrinol. Metab. 79, 171.
      Taylor, A., et al. 1993. Biochemistry 32, 784.
      Ishida, J.I., et al. 1984. J. Chromatogr. 305, 381.
      Umezawa, H. 1982. Annu. Rev. Microbiol. 36, 75.

      Literaturstellen

      Titel
    • Anthony R. White, et al. (2006) Degradation of the alzheimer disease amyloid -peptide by metal-dependent up-regulation of metalloprotease activity. journal of Biological Chemistry 281, 17670-17680.
      		•
      Datenblatt

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision13-May-2013 JSW
      Synonyms[(2S,3R)-3-Amino-2-hydroxy-4-phenylbutanoyl]-Leu
      DescriptionBinds to cell surfaces and inhibits surface aminopeptidases, notably aminopeptidase B and leucine aminopeptidase. Also acts as a potent aminopeptidase N inhibitor. Activates macrophages and T lymphocytes. Has anti-tumor properties. Effective at a concentration of 1-10 µM.
      FormWhite crystalline solid
      CAS number58970-76-6
      RTECSOH2915000
      Chemical formulaC₁₆H₂₄N₂O₄
      Purity>99% by HPLC
      SolubilityDMSO (2 mg/ml) or Methanol (5 mg/ml). Unstable in aqueous solution; dilute just prior to use.
      Storage +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). DMSO and methanol stock solutions are stable for up to 1 month at -20°C.
      Toxicity Standard Handling
      Merck USA index14, 9842
      ReferencesInoue, T., et al. 1994. J. Clin. Endocrinol. Metab. 79, 171.
      Taylor, A., et al. 1993. Biochemistry 32, 784.
      Ishida, J.I., et al. 1984. J. Chromatogr. 305, 381.
      Umezawa, H. 1982. Annu. Rev. Microbiol. 36, 75.
      Citation
    • Anthony R. White, et al. (2006) Degradation of the alzheimer disease amyloid -peptide by metal-dependent up-regulation of metalloprotease activity. journal of Biological Chemistry 281, 17670-17680.
      		•