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528215 Anti-PAI-1 Mouse mAb (MA-33B8)

This Anti-PAI-1 Mouse mAb (MA-33B8) is validated for use in Immunoblotting, Neutralization Studies for the detection of PAI-1.

Anti-PAI-1 Mouse mAb (MA-33B8): SDB (Sicherheitsdatenblätter), Analysenzertifikate und Qualitätszertifikate, Dossiers, Broschüren und andere verfügbare Dokumente.

Synonyme: Anti-Plasminogen Activator Inihibitor-1

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528215
Preis & Verfügbarkeit

Übersicht

Replacement Information

Key Spec Table

Species ReactivityHostAntibody Type
H, RbMMonoclonal Antibody

Preis & Verfügbarkeit

Bestellnummer VerfügbarkeitVerpackung St./Pkg. Preis Menge
528215-100UG
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      		 Kst.-Ampulle 100 μg
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      Description
      OverviewRecognizes the ~50 kDa PAI-1 protein.
      Catalogue Number528215
      Brand Family Calbiochem®
      SynonymsAnti-Plasminogen Activator Inihibitor-1
      References
      ReferencesMontes, R., et al. 2000. Thromb. Haemost. 84, 65.
      Verhamme, I., et al. 1999. J. Biol. Chem. 274, 17511.
      Debrock, S., and Declerck, P.J. 1997. Biochim. Biophys. Acta 1337, 257.
      Product Information
      FormLiquid
      FormulationIn 100 mM NaCl, 50 mM sodium phosphate buffer, pH 7.4.
      PreservativeNone
      Quality LevelMQ100
      Applications
      Application ReferencesNeutralization Studies Verhamme, I., et al. 1999. J. Biol. Chem. 274, 17511.
      Key Applications Immunoblotting (Western Blotting)
      Neutralization Studies
      Application NotesImmunoblotting (10 µg/ml)
      Neutralization Studies (see application references)
      Application CommentsRapidly inactivates PAI-1 (Plasminogen Activator Inhibitor-1) to the latent form. Like the native latent form, PAI-1 inactivated by antibody was protected from cleavage by elastase. Also shown to reduce renal fibrin deposits in a rabbit model of endotoxemia. Variables associated with assay conditions will dictate the proper working dilution.
      Biological Information
      Immunogenhuman tPA-PAI-1 complex
      ImmunogenHuman
      CloneMA-33B8
      HostMouse
      Purity≥ 90% by SDS-PAGE
      IsotypeIgG
      Species Reactivity
      • Human
      • Rabbit
      Antibody TypeMonoclonal Antibody
      Concentration Label Please refer to vial label for lot-specific concentration
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage ≤ -70°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Bestellnummer GTIN
      528215-100UG 04055977196511

      Documentation

      Anti-PAI-1 Mouse mAb (MA-33B8) SDB

      Titel

      Sicherheitsdatenblatt (SDB) 

      Anti-PAI-1 Mouse mAb (MA-33B8) Analysenzertifikate

      TitelChargennummer
      528215

      Literatur

      Übersicht
      Montes, R., et al. 2000. Thromb. Haemost. 84, 65.
      Verhamme, I., et al. 1999. J. Biol. Chem. 274, 17511.
      Debrock, S., and Declerck, P.J. 1997. Biochim. Biophys. Acta 1337, 257.
      Datenblatt

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision10-March-2009 JSW
      SynonymsAnti-Plasminogen Activator Inihibitor-1
      ApplicationImmunoblotting (10 µg/ml)
      Neutralization Studies (see application references)
      DescriptionPurified mouse monoclonal antibody. Recognizes the ~50 kDa PAI-1 protein.
      HostMouse
      Immunogen speciesHuman
      Immunogenhuman tPA-PAI-1 complex
      CloneMA-33B8
      IsotypeIgG
      Specieshuman, rabbit
      FormLiquid
      FormulationIn 100 mM NaCl, 50 mM sodium phosphate buffer, pH 7.4.
      Concentration Label Please refer to vial label for lot-specific concentration
      Purity≥ 90% by SDS-PAGE
      PreservativeNone
      CommentsRapidly inactivates PAI-1 (Plasminogen Activator Inhibitor-1) to the latent form. Like the native latent form, PAI-1 inactivated by antibody was protected from cleavage by elastase. Also shown to reduce renal fibrin deposits in a rabbit model of endotoxemia. Variables associated with assay conditions will dictate the proper working dilution.
      Storage Avoid freeze/thaw
      ≤ -70°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Toxicity Standard Handling
      ReferencesMontes, R., et al. 2000. Thromb. Haemost. 84, 65.
      Verhamme, I., et al. 1999. J. Biol. Chem. 274, 17511.
      Debrock, S., and Declerck, P.J. 1997. Biochim. Biophys. Acta 1337, 257.
      Application referencesNeutralization Studies Verhamme, I., et al. 1999. J. Biol. Chem. 274, 17511.