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MABE570 Anti-N-CoR1, clone 7A7A9 Antibody

Anti-N-CoR1, clone 7A7A9 Antibody detects level of N-CoR1 & has been published & validated for use in N-CoR1.

Anti-N-CoR1, clone 7A7A9 Antibody: SDB (Sicherheitsdatenblätter), Analysenzertifikate und Qualitätszertifikate, Dossiers, Broschüren und andere verfügbare Dokumente.
Research Category: Epigenetics & Nuclear Function Research Sub-Category: Chromatin Biology Gene Symbol: NCOR1, KIAA1047 UniProt Number: O75376
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MABE570
100 µL  
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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HIHCMAscitesMonoclonal Antibody
      Description
      Catalogue NumberMABE570
      DescriptionAnti-N-CoR1, clone 7A7A9 Antibody
      Alternate Names
      • Nuclear receptor corepressor 1
      • N-CoR
      • N-CoR1
      Background InformationNuclear receptor corepressor 1 (N-CoR or N-CoR1), and encoded by the gene name NCOR, mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. N-CoR1 is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. N-CoR1 is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17.
      References
      Product Information
      FormatAscites
      PresentationMouse monoclonal IgG1 ascitic fluid containing up to 0.1% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-N-CoR1, clone 7A7A9 Antibody detects level of N-CoR1 & has been published & validated for use in N-CoR1.
      Key Applications
      • Immunohistochemistry
      Biological Information
      ImmunogenPurified recombinant fragment of human N-CoR1 expressed in E. Coli
      Clone7A7A9
      HostMouse
      IsotypeIgG1
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Gene Symbol
      • NCOR1
      • KIAA1047
      Purification MethodUnpurified
      UniProt Number
      Molecular Weight270 kDa calculated
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceImmunohistochemistry Analysis: A 1:200-1,000 dilution from a representative lot detected N-CoR1 in human cerebra and breast carcinoma tissues.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at -20°C from date of receipt.
      Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Bestellnummer GTIN
      MABE570 04053252957291